Manganese »
PDB 4wl8-4xwt »
4wtc »
Manganese in PDB 4wtc: Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Cdp, MN2+ and Symmetrical Primer Template 5'-Agaaauuu
Enzymatic activity of Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Cdp, MN2+ and Symmetrical Primer Template 5'-Agaaauuu
All present enzymatic activity of Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Cdp, MN2+ and Symmetrical Primer Template 5'-Agaaauuu:
2.7.7.48;
2.7.7.48;
Protein crystallography data
The structure of Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Cdp, MN2+ and Symmetrical Primer Template 5'-Agaaauuu, PDB code: 4wtc
was solved by
T.E.Edwards,
T.C.Appleby,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 50.00 / 2.75 |
| Space group | P 65 |
| Cell size a, b, c (Å), α, β, γ (°) | 141.340, 141.340, 90.800, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 17.8 / 22.9 |
Other elements in 4wtc:
The structure of Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Cdp, MN2+ and Symmetrical Primer Template 5'-Agaaauuu also contains other interesting chemical elements:
| Chlorine | (Cl) | 1 atom |
Manganese Binding Sites:
The binding sites of Manganese atom in the Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Cdp, MN2+ and Symmetrical Primer Template 5'-Agaaauuu
(pdb code 4wtc). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total 3 binding sites of Manganese where determined in the Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Cdp, MN2+ and Symmetrical Primer Template 5'-Agaaauuu, PDB code: 4wtc:
Jump to Manganese binding site number: 1; 2; 3;
In total 3 binding sites of Manganese where determined in the Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Cdp, MN2+ and Symmetrical Primer Template 5'-Agaaauuu, PDB code: 4wtc:
Jump to Manganese binding site number: 1; 2; 3;
Manganese binding site 1 out of 3 in 4wtc
Go back to
Manganese Binding Sites List in 4wtc
Manganese binding site 1 out
of 3 in the Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Cdp, MN2+ and Symmetrical Primer Template 5'-Agaaauuu
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 1 of Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Cdp, MN2+ and Symmetrical Primer Template 5'-Agaaauuu within 5.0Å range:
|
Manganese binding site 2 out of 3 in 4wtc
Go back to
Manganese Binding Sites List in 4wtc
Manganese binding site 2 out
of 3 in the Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Cdp, MN2+ and Symmetrical Primer Template 5'-Agaaauuu
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 2 of Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Cdp, MN2+ and Symmetrical Primer Template 5'-Agaaauuu within 5.0Å range:
|
Manganese binding site 3 out of 3 in 4wtc
Go back to
Manganese Binding Sites List in 4wtc
Manganese binding site 3 out
of 3 in the Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Cdp, MN2+ and Symmetrical Primer Template 5'-Agaaauuu
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 3 of Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Cdp, MN2+ and Symmetrical Primer Template 5'-Agaaauuu within 5.0Å range:
|
Reference:
T.C.Appleby,
J.Perry,
E.Murakami,
O.Barauskas,
J.Feng,
A.Cho,
D.Fox Iii,
D.R.Wetmore,
M.E.Mcgrath,
A.S.Ray,
M.J.Sofia,
S.Swaminathan,
T.E.Edwards.
Structural Basis For Rna Replication By the Hepatitis C Virus Polymerase To Be Published.
Page generated: Tue Dec 15 04:33:00 2020
Last articles
Zn in 8WB0Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
