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Atomistry » Manganese » PDB 4u87-4wiu » 4u8z | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Manganese » PDB 4u87-4wiu » 4u8z » |
Manganese in PDB 4u8z: Crystal Structure of MST3 with A Pyrrolopyrimidine Inhibitor (Pf- 06447475)Enzymatic activity of Crystal Structure of MST3 with A Pyrrolopyrimidine Inhibitor (Pf- 06447475)
All present enzymatic activity of Crystal Structure of MST3 with A Pyrrolopyrimidine Inhibitor (Pf- 06447475):
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of MST3 with A Pyrrolopyrimidine Inhibitor (Pf- 06447475), PDB code: 4u8z
was solved by
J.Jasti,
X.Song,
M.Griffor,
R.G.Kurumbail,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Manganese Binding Sites:
The binding sites of Manganese atom in the Crystal Structure of MST3 with A Pyrrolopyrimidine Inhibitor (Pf- 06447475)
(pdb code 4u8z). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Crystal Structure of MST3 with A Pyrrolopyrimidine Inhibitor (Pf- 06447475), PDB code: 4u8z: Manganese binding site 1 out of 1 in 4u8zGo back to Manganese Binding Sites List in 4u8z
Manganese binding site 1 out
of 1 in the Crystal Structure of MST3 with A Pyrrolopyrimidine Inhibitor (Pf- 06447475)
Mono view Stereo pair view
Reference:
J.L.Henderson,
B.L.Kormos,
M.M.Hayward,
K.J.Coffman,
J.Jasti,
R.G.Kurumbail,
T.T.Wager,
P.R.Verhoest,
G.S.Noell,
Y.Chen,
E.Needle,
Z.Berger,
S.J.Steyn,
C.Houle,
W.D.Hirst,
P.Galatsis.
Discovery and Preclinical Profiling of 3-[4-(Morpholin-4-Yl)-7H-Pyrrolo[2, 3-D]Pyrimidin-5-Yl]Benzonitrile (Pf-06447475), A Highly Potent, Selective, Brain Penetrant, and in Vivo Active LRRK2 Kinase Inhibitor. J.Med.Chem. V. 58 419 2015.
Page generated: Tue Dec 15 04:29:22 2020
ISSN: ISSN 0022-2623 PubMed: 25353650 DOI: 10.1021/JM5014055 |
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