Manganese in PDB 4r43: Crystal Structure Analysis of Mtb Pepck

All present enzymatic activity of Crystal Structure Analysis of Mtb Pepck:
4.1.1.32;

The structure of Crystal Structure Analysis of Mtb Pepck, PDB code: 4r43 was solved by J.Brynda, J.Dostal, I.Pichova, J.Snasel, J.Fanfrlik, I.Machova, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.55 / 1.80
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	103.358, 124.696, 121.466, 90.00, 90.00, 90.00
R / Rfree (%)	20.7 / 24.3

The binding sites of Manganese atom in the Crystal Structure Analysis of Mtb Pepck (pdb code 4r43). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Crystal Structure Analysis of Mtb Pepck, PDB code: 4r43:

Manganese binding site 1 out of 1 in the Crystal Structure Analysis of Mtb Pepck


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Crystal Structure Analysis of Mtb Pepck within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn702 b:35.7 occ:1.00 OG1 A:THR276 2.0 34.3 1.0 O A:HOH819 2.0 27.8 1.0 O1B A:GDP701 2.2 31.7 1.0 O A:HOH820 2.2 24.9 1.0 O A:HOH822 2.3 39.0 1.0 O A:HOH821 2.3 35.9 1.0 CB A:THR276 3.2 36.4 1.0 PB A:GDP701 3.4 34.0 1.0 O3B A:GDP701 3.6 32.7 1.0 O4 A:PO4707 3.7 78.4 1.0 N A:THR276 3.9 33.7 1.0 O2A A:GDP701 4.1 30.7 1.0 CA A:THR276 4.1 33.1 1.0 OD2 A:ASP295 4.2 44.6 1.0 CG2 A:THR276 4.3 35.5 1.0 O2B A:GDP701 4.3 35.4 1.0 O3A A:GDP701 4.5 34.7 1.0 O A:ASP295 4.6 31.7 1.0 PA A:GDP701 4.7 33.4 1.0 CB A:LYS275 4.8 30.5 1.0 CG A:ASP295 4.8 36.7 1.0 C A:LYS275 4.9 32.5 1.0 NZ A:LYS275 5.0 31.9 1.0 CE A:LYS275 5.0 36.0 1.0

I.Machova, J.Snasel, J.Dostal, J.Brynda, J.Fanfrlik, M.Singh, J.Tarabek, O.Vanek, L.Bednarova, I.Pichova. Structural and Functional Studies of Phosphoenolpyruvate Carboxykinase From Mycobacterium Tuberculosis. Plos One V. 10 20682 2015.
ISSN: ESSN 1932-6203
PubMed: 25798914
DOI: 10.1371/JOURNAL.PONE.0120682