Atomistry » Manganese » PDB 4mu4-4nx7 » 4nro
Atomistry »
  Manganese »
    PDB 4mu4-4nx7 »
      4nro »

Manganese in PDB 4nro: Crystal Structure of Human ALKBH5 in Complex with Alpha-Ketoglutarate

Protein crystallography data

The structure of Crystal Structure of Human ALKBH5 in Complex with Alpha-Ketoglutarate, PDB code: 4nro was solved by C.Feng, Z.Chen, Y.Liu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 2.30
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 56.177, 56.177, 144.940, 90.00, 90.00, 90.00
R / Rfree (%) 23.7 / 25.6

Manganese Binding Sites:

The binding sites of Manganese atom in the Crystal Structure of Human ALKBH5 in Complex with Alpha-Ketoglutarate (pdb code 4nro). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Crystal Structure of Human ALKBH5 in Complex with Alpha-Ketoglutarate, PDB code: 4nro:

Manganese binding site 1 out of 1 in 4nro

Go back to Manganese Binding Sites List in 4nro
Manganese binding site 1 out of 1 in the Crystal Structure of Human ALKBH5 in Complex with Alpha-Ketoglutarate


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Crystal Structure of Human ALKBH5 in Complex with Alpha-Ketoglutarate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mn301

b:54.5
occ:1.00
OD1 A:ASP206 2.2 52.5 1.0
O1 A:AKG302 2.2 58.3 1.0
NE2 A:HIS266 2.2 51.9 1.0
NE2 A:HIS204 2.2 55.0 1.0
O5 A:AKG302 2.3 61.8 1.0
O A:HOH401 2.4 52.9 1.0
C2 A:AKG302 2.7 61.4 1.0
C1 A:AKG302 2.8 59.9 1.0
CE1 A:HIS266 3.0 49.5 1.0
CE1 A:HIS204 3.0 53.4 1.0
CG A:ASP206 3.2 51.6 1.0
CD2 A:HIS204 3.4 50.9 1.0
CD2 A:HIS266 3.4 48.0 1.0
OD2 A:ASP206 3.6 50.7 1.0
C3 A:AKG302 4.0 64.6 1.0
O2 A:AKG302 4.1 57.6 1.0
ND1 A:HIS266 4.2 48.6 1.0
ND1 A:HIS204 4.2 49.8 1.0
O A:HOH476 4.3 73.9 1.0
O A:HOH445 4.4 63.1 1.0
CG A:HIS204 4.4 50.6 1.0
CG A:HIS266 4.4 47.1 1.0
C4 A:AKG302 4.5 61.5 1.0
CB A:ASP206 4.6 50.3 1.0
N A:ASP206 4.9 46.2 1.0
CA A:ASP206 4.9 48.1 1.0

Reference:

C.Feng, Y.Liu, G.Wang, Z.Deng, Q.Zhang, W.Wu, Y.Tong, C.Cheng, Z.Chen. Crystal Structures of Human Rna Demethylase ALKBH5 Reveal Basis For Substrate Recognition J.Biol.Chem. 2014.
ISSN: ESSN 1083-351X
DOI: 10.1074/JBC.M113.546168
Page generated: Sat Oct 5 20:35:14 2024

Last articles

Cl in 7XGN
Cl in 7XHH
Cl in 7XGM
Cl in 7XHK
Cl in 7XGL
Cl in 7XGI
Cl in 7XFY
Cl in 7XFA
Cl in 7XFX
Cl in 7XFW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy