Manganese in PDB 4nid: Crystal Structure of Alkb Protein with Cofactors Bound to Dsdna Containing M6A

All present enzymatic activity of Crystal Structure of Alkb Protein with Cofactors Bound to Dsdna Containing M6A:
1.14.11.33;

The structure of Crystal Structure of Alkb Protein with Cofactors Bound to Dsdna Containing M6A, PDB code: 4nid was solved by C.X.Zhu, C.Q.Yi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.58
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	41.416, 75.907, 52.088, 90.00, 108.84, 90.00
R / Rfree (%)	17.9 / 19.7

The binding sites of Manganese atom in the Crystal Structure of Alkb Protein with Cofactors Bound to Dsdna Containing M6A (pdb code 4nid). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Crystal Structure of Alkb Protein with Cofactors Bound to Dsdna Containing M6A, PDB code: 4nid:

Manganese binding site 1 out of 1 in the Crystal Structure of Alkb Protein with Cofactors Bound to Dsdna Containing M6A


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Crystal Structure of Alkb Protein with Cofactors Bound to Dsdna Containing M6A within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn301 b:12.3 occ:1.00 OD1 A:ASP133 2.1 13.6 1.0 NE2 A:HIS131 2.2 11.5 1.0 O1 A:AKG302 2.2 18.2 1.0 NE2 A:HIS187 2.2 11.8 1.0 O5 A:AKG302 2.4 15.4 1.0 O A:HOH421 2.4 18.4 1.0 C1 A:AKG302 3.0 19.2 1.0 C2 A:AKG302 3.1 18.1 1.0 CG A:ASP133 3.1 14.5 1.0 CE1 A:HIS131 3.1 11.5 1.0 CD2 A:HIS131 3.1 11.7 1.0 CE1 A:HIS187 3.1 12.1 1.0 CD2 A:HIS187 3.2 11.8 1.0 OD2 A:ASP133 3.4 15.1 1.0 O A:HOH429 4.0 18.0 1.0 O2 A:AKG302 4.2 21.4 1.0 ND1 A:HIS131 4.2 11.7 1.0 O A:HOH441 4.2 20.0 1.0 N1 B:6MA8 4.2 13.3 1.0 CG A:HIS131 4.3 11.9 1.0 ND1 A:HIS187 4.3 12.2 1.0 CG A:HIS187 4.4 11.9 1.0 CB A:ASP133 4.4 14.7 1.0 C2 B:6MA8 4.4 12.9 1.0 C3 A:AKG302 4.5 17.3 1.0 C6 B:6MA8 4.6 13.2 1.0 CZ2 A:TRP178 4.7 13.9 1.0 N A:ASP133 4.8 14.4 1.0 N3 B:6MA8 4.9 12.6 1.0 CA A:ASP133 5.0 15.0 1.0

C.Zhu, C.Yi. Switching Demethylation Activities Between Alkb Family Rna/Dna Demethylases Through Exchange of Active-Site Residues. Angew.Chem.Int.Ed.Engl. V. 53 3659 2014.
ISSN: ISSN 1433-7851
PubMed: 24596302
DOI: 10.1002/ANIE.201310050