Manganese in PDB 4mvr: Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel

The structure of Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel, PDB code: 4mvr was solved by L.Tang, T.M.Gamal El-Din, J.Payandeh, Q.M.Gilbert, T.M.Heard, T.Scheuer, N.Zheng, W.A.Catterall, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.05 / 3.20
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	177.440, 177.535, 130.785, 90.00, 132.70, 90.00
R / Rfree (%)	23.9 / 26.2

The binding sites of Manganese atom in the Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel (pdb code 4mvr). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel, PDB code: 4mvr:

Manganese binding site 1 out of 1 in the Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn1301 b:0.7 occ:1.00 O C:HOH1401 1.9 0.7 1.0 O A:HOH1401 1.9 90.2 1.0 O A:HOH1402 1.9 78.9 1.0 O D:HOH1401 1.9 64.2 1.0 O C:HOH1402 1.9 58.8 1.0 O B:HOH1401 2.0 58.7 1.0 OD1 C:ASP1177 4.3 43.3 1.0 OD1 D:ASP1177 4.4 50.5 1.0 O C:LEU1176 4.5 44.8 1.0 OD1 A:ASP1177 4.5 48.0 1.0 O A:LEU1176 4.5 46.4 1.0 N A:ASP1178 4.5 56.2 1.0 N B:ASP1178 4.5 47.4 1.0 OD1 B:ASP1177 4.5 55.8 1.0 O D:LEU1176 4.5 38.2 1.0 N C:ASP1178 4.5 50.8 1.0 N D:ASP1178 4.5 43.7 1.0 O B:LEU1176 4.6 41.2 1.0 CA C:ASP1177 4.8 55.7 1.0 CA A:ASP1177 4.9 55.5 1.0 CA D:ASP1177 4.9 52.8 1.0 CA B:ASP1177 4.9 55.2 1.0

L.Tang, T.M.Gamal El-Din, J.Payandeh, G.Q.Martinez, T.M.Heard, T.Scheuer, N.Zheng, W.A.Catterall. Structural Basis For CA2+ Selectivity of A Voltage-Gated Calcium Channel. Nature V. 505 56 2014.
ISSN: ISSN 0028-0836
PubMed: 24270805
DOI: 10.1038/NATURE12775