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Atomistry » Manganese » PDB 4b5i-4dec » 4bqw » |
Manganese in PDB 4bqw: Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with Mn(II) and 2- (4-Hydroxy-2-Oxo-1,2-Dihydroquinoline-3-Carboxamido)Acetic AcidProtein crystallography data
The structure of Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with Mn(II) and 2- (4-Hydroxy-2-Oxo-1,2-Dihydroquinoline-3-Carboxamido)Acetic Acid, PDB code: 4bqw
was solved by
R.Chowdhury,
C.J.Schofield,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Manganese Binding Sites:
The binding sites of Manganese atom in the Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with Mn(II) and 2- (4-Hydroxy-2-Oxo-1,2-Dihydroquinoline-3-Carboxamido)Acetic Acid
(pdb code 4bqw). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with Mn(II) and 2- (4-Hydroxy-2-Oxo-1,2-Dihydroquinoline-3-Carboxamido)Acetic Acid, PDB code: 4bqw: Manganese binding site 1 out of 1 in 4bqwGo back to Manganese Binding Sites List in 4bqw
Manganese binding site 1 out
of 1 in the Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with Mn(II) and 2- (4-Hydroxy-2-Oxo-1,2-Dihydroquinoline-3-Carboxamido)Acetic Acid
Mono view Stereo pair view
Reference:
R.Chowdhury,
J.I.Candela-Lena,
M.C.Chan,
D.J.Greenald,
K.K.Yeoh,
Y.M.Tian,
M.A.Mcdonough,
A.Tumber,
N.R.Rose,
A.Conejo-Garcia,
M.Demetriades,
S.Mathavan,
A.Kawamura,
M.K.Lee,
F.Van Eeden,
C.W.Pugh,
P.J.Ratcliffe,
C.J.Schofield.
Selective Small Molecule Probes For the Hypoxia Inducible Factor (Hif) Prolyl Hydroxylases. Acs Chem. Biol. V. 8 1488 2013.
Page generated: Tue Dec 15 04:18:30 2020
ISSN: ESSN 1554-8937 PubMed: 23683440 DOI: 10.1021/CB400088Q |
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