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Atomistry » Manganese » PDB 3x30-4b5h » 4aw1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Manganese » PDB 3x30-4b5h » 4aw1 » |
Manganese in PDB 4aw1: Human PDK1 Kinase Domain in Complex with Allosteric Compound PS210 Bound to the Pif-PocketEnzymatic activity of Human PDK1 Kinase Domain in Complex with Allosteric Compound PS210 Bound to the Pif-Pocket
All present enzymatic activity of Human PDK1 Kinase Domain in Complex with Allosteric Compound PS210 Bound to the Pif-Pocket:
2.7.11.1; Protein crystallography data
The structure of Human PDK1 Kinase Domain in Complex with Allosteric Compound PS210 Bound to the Pif-Pocket, PDB code: 4aw1
was solved by
J.O.Schulze,
K.Busschots,
L.A.Lopez-Garcia,
C.Lammi,
A.Stroba,
S.Zeuzem,
A.Piiper,
P.M.Alzari,
S.Neimanis,
J.M.Arencibia,
M.Engel,
R.M.Biondi,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4aw1:
The structure of Human PDK1 Kinase Domain in Complex with Allosteric Compound PS210 Bound to the Pif-Pocket also contains other interesting chemical elements:
Manganese Binding Sites:
The binding sites of Manganese atom in the Human PDK1 Kinase Domain in Complex with Allosteric Compound PS210 Bound to the Pif-Pocket
(pdb code 4aw1). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Human PDK1 Kinase Domain in Complex with Allosteric Compound PS210 Bound to the Pif-Pocket, PDB code: 4aw1: Manganese binding site 1 out of 1 in 4aw1Go back to Manganese Binding Sites List in 4aw1
Manganese binding site 1 out
of 1 in the Human PDK1 Kinase Domain in Complex with Allosteric Compound PS210 Bound to the Pif-Pocket
Mono view Stereo pair view
Reference:
K.Busschots,
L.A.Lopez-Garcia,
C.Lammi,
A.Stroba,
S.Zeuzem,
A.Piiper,
P.M.Alzari,
S.Neimanis,
J.M.Arencibia,
M.Engel,
J.O.Schulze,
R.M.Biondi.
Substrate-Selective Inhibition of Protein Kinase PDK1 By Small Compounds That Bind to the Pif-Pocket Allosteric Docking Site. Chem.Biol. V. 19 1152 2012.
Page generated: Tue Dec 15 04:18:16 2020
ISSN: ISSN 1074-5521 PubMed: 22999883 DOI: 10.1016/J.CHEMBIOL.2012.07.017 |
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