Atomistry » Manganese » PDB 3uag-3vnm » 3v0q
Atomistry »
  Manganese »
    PDB 3uag-3vnm »
      3v0q »

Manganese in PDB 3v0q: Crystal Structure of the Fucosylgalactoside Alpha N- Acetylgalactosaminyltransferase (Gta, Cisab Mutant L266G, G268A) in Complex with Udp and H-Antigen Acceptor

Enzymatic activity of Crystal Structure of the Fucosylgalactoside Alpha N- Acetylgalactosaminyltransferase (Gta, Cisab Mutant L266G, G268A) in Complex with Udp and H-Antigen Acceptor

All present enzymatic activity of Crystal Structure of the Fucosylgalactoside Alpha N- Acetylgalactosaminyltransferase (Gta, Cisab Mutant L266G, G268A) in Complex with Udp and H-Antigen Acceptor:
2.4.1.37; 2.4.1.40;

Protein crystallography data

The structure of Crystal Structure of the Fucosylgalactoside Alpha N- Acetylgalactosaminyltransferase (Gta, Cisab Mutant L266G, G268A) in Complex with Udp and H-Antigen Acceptor, PDB code: 3v0q was solved by M.M.Palcic, R.Jorgensen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.94 / 1.80
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 78.100, 153.670, 52.500, 90.00, 90.00, 90.00
R / Rfree (%) 15.1 / 19.1

Manganese Binding Sites:

The binding sites of Manganese atom in the Crystal Structure of the Fucosylgalactoside Alpha N- Acetylgalactosaminyltransferase (Gta, Cisab Mutant L266G, G268A) in Complex with Udp and H-Antigen Acceptor (pdb code 3v0q). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Crystal Structure of the Fucosylgalactoside Alpha N- Acetylgalactosaminyltransferase (Gta, Cisab Mutant L266G, G268A) in Complex with Udp and H-Antigen Acceptor, PDB code: 3v0q:
Jump to Manganese binding site number: 1; 2;

Manganese binding site 1 out of 2 in 3v0q

Go back to Manganese Binding Sites List in 3v0q
Manganese binding site 1 out of 2 in the Crystal Structure of the Fucosylgalactoside Alpha N- Acetylgalactosaminyltransferase (Gta, Cisab Mutant L266G, G268A) in Complex with Udp and H-Antigen Acceptor


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Crystal Structure of the Fucosylgalactoside Alpha N- Acetylgalactosaminyltransferase (Gta, Cisab Mutant L266G, G268A) in Complex with Udp and H-Antigen Acceptor within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mn401

b:16.4
occ:1.00
OD2 A:ASP211 2.2 13.5 1.0
O2A A:UDP402 2.2 15.4 1.0
O2B A:UDP402 2.3 21.1 1.0
OD1 A:ASP213 2.3 14.1 1.0
O A:HOH619 2.3 17.3 1.0
OD2 A:ASP213 2.5 15.1 1.0
CG A:ASP213 2.7 13.8 1.0
CG A:ASP211 3.2 11.5 1.0
PB A:UDP402 3.4 25.7 1.0
PA A:UDP402 3.5 16.5 1.0
CB A:ASP211 3.5 9.5 1.0
O3A A:UDP402 3.6 18.2 1.0
O A:HOH684 3.7 30.4 1.0
O3' A:UDP402 3.8 15.3 1.0
O A:HOH606 4.1 25.7 1.0
O1B A:UDP402 4.1 23.5 1.0
NZ A:LYS346 4.1 23.0 1.0
C5' A:UDP402 4.2 12.8 1.0
CB A:ASP213 4.2 11.8 1.0
OD1 A:ASP211 4.3 9.3 1.0
O5' A:UDP402 4.4 12.2 1.0
C3' A:UDP402 4.5 15.2 1.0
O1A A:UDP402 4.5 18.9 1.0
O3B A:UDP402 4.6 26.1 1.0
C4' A:UDP402 4.8 14.8 1.0
O A:HOH613 4.8 17.8 1.0
O A:ASP213 4.9 11.1 1.0
N A:ASP213 4.9 11.6 1.0
SD A:MET214 4.9 11.9 1.0
CA A:ASP211 4.9 8.2 1.0
CE A:LYS346 5.0 24.4 1.0

Manganese binding site 2 out of 2 in 3v0q

Go back to Manganese Binding Sites List in 3v0q
Manganese binding site 2 out of 2 in the Crystal Structure of the Fucosylgalactoside Alpha N- Acetylgalactosaminyltransferase (Gta, Cisab Mutant L266G, G268A) in Complex with Udp and H-Antigen Acceptor


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Crystal Structure of the Fucosylgalactoside Alpha N- Acetylgalactosaminyltransferase (Gta, Cisab Mutant L266G, G268A) in Complex with Udp and H-Antigen Acceptor within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mn401

b:12.8
occ:1.00
OD2 B:ASP211 2.1 11.7 1.0
O2B B:UDP402 2.1 14.4 1.0
O B:HOH553 2.2 8.8 1.0
O2A B:UDP402 2.2 13.3 1.0
OD1 B:ASP213 2.3 12.8 1.0
OD2 B:ASP213 2.5 14.8 1.0
CG B:ASP213 2.7 12.9 1.0
CG B:ASP211 3.2 11.3 1.0
PB B:UDP402 3.3 16.7 1.0
PA B:UDP402 3.4 13.6 1.0
CB B:ASP211 3.5 8.9 1.0
O3A B:UDP402 3.5 14.8 1.0
O3' B:UDP402 3.8 11.6 1.0
O B:HOH544 3.8 19.8 1.0
O1B B:UDP402 3.9 18.1 1.0
O B:HOH669 4.1 27.9 1.0
NZ B:LYS346 4.1 16.6 1.0
C5' B:UDP402 4.2 9.3 1.0
CB B:ASP213 4.2 12.4 1.0
OD1 B:ASP211 4.3 11.5 1.0
O5' B:UDP402 4.3 9.7 1.0
O1A B:UDP402 4.4 16.3 1.0
C3' B:UDP402 4.5 10.9 1.0
O3B B:UDP402 4.5 19.0 1.0
O B:HOH551 4.8 14.7 1.0
C4' B:UDP402 4.8 10.0 1.0
O B:HOH612 4.9 15.2 1.0
N B:ASP213 4.9 10.3 1.0
CA B:ASP211 4.9 7.6 1.0
SD B:MET214 4.9 12.7 1.0
O B:ASP213 5.0 10.9 1.0

Reference:

R.Jrgensen, T.Pesnot, H.J.Lee, M.M.Palcic, G.K.Wagner. Base-Modified Donor Analogues Reveal Novel Dynamic Features of A Glycosyltransferase. J.Biol.Chem. V. 288 26201 2013.
ISSN: ISSN 0021-9258
PubMed: 23836908
DOI: 10.1074/JBC.M113.465963
Page generated: Tue Dec 15 04:16:38 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy