Manganese in PDB 3qid: Crystal Structures and Functional Analysis of Murine Norovirus Rna- Dependent Rna Polymerase

The structure of Crystal Structures and Functional Analysis of Murine Norovirus Rna- Dependent Rna Polymerase, PDB code: 3qid was solved by K.H.Kim, A.Intekhab, J.H.Lee, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.07 / 2.50
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	120.557, 196.262, 109.339, 90.00, 114.23, 90.00
R / Rfree (%)	19.9 / 24.5

The binding sites of Manganese atom in the Crystal Structures and Functional Analysis of Murine Norovirus Rna- Dependent Rna Polymerase (pdb code 3qid). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 3 binding sites of Manganese where determined in the Crystal Structures and Functional Analysis of Murine Norovirus Rna- Dependent Rna Polymerase, PDB code: 3qid:
Jump to Manganese binding site number: 1; 2; 3;

Manganese binding site 1 out of 3 in the Crystal Structures and Functional Analysis of Murine Norovirus Rna- Dependent Rna Polymerase


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Crystal Structures and Functional Analysis of Murine Norovirus Rna- Dependent Rna Polymerase within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn532 b:55.2 occ:1.00 O A:HOH655 2.3 15.4 1.0 O A:HOH664 2.3 14.4 1.0 OD2 A:ASP347 2.4 20.4 1.0 O A:HOH648 2.6 20.9 1.0 O A:HOH620 2.8 43.2 1.0 OD2 A:ASP243 3.3 17.6 1.0 CG A:ASP347 3.5 19.7 1.0 OD1 A:ASP243 4.0 16.4 1.0 CG A:ASP243 4.0 15.7 1.0 OD1 A:ASP347 4.0 22.2 1.0 O A:SER392 4.2 21.0 1.0 N A:GLU348 4.3 17.5 1.0 O A:GLU348 4.4 16.0 1.0 CA A:ASP347 4.5 18.2 1.0 CB A:ASP347 4.5 18.4 1.0 C A:SER392 4.8 21.2 1.0 O A:HOH673 4.8 32.2 1.0 C A:ASP347 4.9 18.0 1.0

Manganese binding site 2 out of 3 in the Crystal Structures and Functional Analysis of Murine Norovirus Rna- Dependent Rna Polymerase


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Crystal Structures and Functional Analysis of Murine Norovirus Rna- Dependent Rna Polymerase within 5.0Å range: probe atom residue distance (Å) B Occ B:Mn529 b:74.3 occ:1.00 OD2 B:ASP347 2.2 25.5 1.0 O B:HOH642 2.3 29.3 1.0 O B:HOH621 2.6 21.8 1.0 CG B:ASP347 3.2 23.4 1.0 OD1 B:ASP243 3.6 25.6 1.0 O B:HOH650 3.6 34.7 1.0 OD1 B:ASP347 3.7 25.0 1.0 OD2 B:ASP243 4.1 26.4 1.0 CG B:ASP243 4.2 25.2 1.0 O B:SER392 4.3 29.6 1.0 CB B:ASP347 4.3 21.8 1.0 N B:GLU348 4.3 21.9 1.0 CA B:ASP347 4.4 21.7 1.0 O B:GLU348 4.5 22.6 1.0 O B:HOH630 4.7 22.3 1.0 C B:SER392 4.8 29.8 1.0 C B:ASP347 4.8 21.8 1.0

Manganese binding site 3 out of 3 in the Crystal Structures and Functional Analysis of Murine Norovirus Rna- Dependent Rna Polymerase


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 3 of Crystal Structures and Functional Analysis of Murine Norovirus Rna- Dependent Rna Polymerase within 5.0Å range: probe atom residue distance (Å) B Occ C:Mn527 b:72.3 occ:1.00 OD2 C:ASP347 2.3 24.8 1.0 O C:HOH633 2.6 24.5 1.0 OD2 C:ASP243 3.1 22.8 1.0 O C:HOH644 3.5 28.3 1.0 CG C:ASP347 3.5 22.1 1.0 O C:SER392 3.7 28.6 1.0 CG C:ASP243 3.7 22.0 1.0 OD1 C:ASP243 3.7 21.1 1.0 O C:GLU348 4.0 20.6 1.0 OD1 C:ASP347 4.2 24.9 1.0 N C:GLU348 4.2 20.2 1.0 O C:HOH573 4.3 17.7 1.0 CA C:ASP347 4.5 20.3 1.0 C C:SER392 4.5 28.5 1.0 CB C:ASP347 4.6 20.2 1.0 O C:HOH560 4.6 13.7 1.0 C C:ASP347 4.8 20.1 1.0 CA C:PHE393 4.9 26.6 1.0 C C:GLU348 4.9 20.4 1.0

J.H.Lee, I.Alam, K.R.Han, S.Cho, S.Shin, S.Kang, J.M.Yang, K.H.Kim. Crystal Structures of Murine Norovirus-1 Rna-Dependent Rna Polymerase. J.Gen.Virol. V. 92 1607 2011.
ISSN: ISSN 0022-1317
PubMed: 21471315
DOI: 10.1099/VIR.0.031104-0