Manganese in PDB 3p71: Crystal Structure of the Complex of Lcmt-1 and PP2A

All present enzymatic activity of Crystal Structure of the Complex of Lcmt-1 and PP2A:
3.1.3.16;

The structure of Crystal Structure of the Complex of Lcmt-1 and PP2A, PDB code: 3p71 was solved by Y.Xing, V.Stanevich, K.A.Satyshur, L.Jiang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.27 / 2.70
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	48.802, 65.305, 193.092, 90.00, 90.00, 90.00
R / Rfree (%)	19.2 / 24.9

The binding sites of Manganese atom in the Crystal Structure of the Complex of Lcmt-1 and PP2A (pdb code 3p71). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Crystal Structure of the Complex of Lcmt-1 and PP2A, PDB code: 3p71:
Jump to Manganese binding site number: 1; 2;

Manganese binding site 1 out of 2 in the Crystal Structure of the Complex of Lcmt-1 and PP2A


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Crystal Structure of the Complex of Lcmt-1 and PP2A within 5.0Å range: probe atom residue distance (Å) B Occ C:Mn501 b:29.3 occ:1.00 O C:HOH631 1.8 34.3 1.0 OD1 C:ASN117 1.9 30.3 1.0 NE2 C:HIS167 2.0 28.1 1.0 ND1 C:HIS241 2.2 32.9 1.0 OD2 C:ASP85 2.4 32.4 1.0 CG C:ASN117 3.0 33.1 1.0 CE1 C:HIS241 3.0 33.3 1.0 CE1 C:HIS167 3.0 27.2 1.0 CD2 C:HIS167 3.0 29.4 1.0 CG C:ASP85 3.2 30.5 1.0 MN C:MN502 3.2 34.8 1.0 CG C:HIS241 3.3 34.0 1.0 OD1 C:ASP85 3.3 30.9 1.0 O T:HOH621 3.4 36.7 1.0 CA C:HIS241 3.6 32.7 1.0 ND2 C:ASN117 3.6 33.4 1.0 CB C:HIS241 3.8 33.8 1.0 OD2 C:ASP57 3.9 33.2 1.0 O C:HIS241 4.0 34.1 1.0 ND1 C:HIS167 4.1 27.6 1.0 CB C:ASN117 4.1 34.6 1.0 NE2 C:HIS241 4.1 35.1 1.0 CG C:HIS167 4.2 28.7 1.0 C C:HIS241 4.3 33.7 1.0 CD2 C:HIS241 4.3 35.2 1.0 CD2 C:HIS118 4.3 31.7 1.0 N C:ASN117 4.3 32.8 1.0 CB C:ASP85 4.5 29.4 1.0 N C:HIS241 4.6 31.9 1.0 O C:LEU199 4.6 38.4 1.0 CG C:ASP57 4.7 32.3 1.0 CA C:ASN117 4.7 33.9 1.0 O T:HOH654 4.8 34.6 1.0 OD1 C:ASP57 4.8 33.1 1.0 N C:HIS118 4.9 32.4 1.0

Manganese binding site 2 out of 2 in the Crystal Structure of the Complex of Lcmt-1 and PP2A


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Crystal Structure of the Complex of Lcmt-1 and PP2A within 5.0Å range: probe atom residue distance (Å) B Occ C:Mn502 b:34.8 occ:1.00 OD2 C:ASP57 1.9 33.2 1.0 OD2 C:ASP85 1.9 32.4 1.0 O T:HOH654 2.2 34.6 1.0 O C:HOH631 2.2 34.3 1.0 NE2 C:HIS59 2.2 28.0 1.0 CE1 C:HIS59 3.0 28.2 1.0 CG C:ASP85 3.1 30.5 1.0 CG C:ASP57 3.1 32.3 1.0 MN C:MN501 3.2 29.3 1.0 CD2 C:HIS59 3.3 27.8 1.0 CB C:ASP85 3.7 29.4 1.0 OD1 C:ASP57 4.0 33.1 1.0 CB C:ASP57 4.0 30.7 1.0 OD1 C:ASP85 4.1 30.9 1.0 O T:HOH621 4.1 36.7 1.0 CD2 C:HIS118 4.1 31.7 1.0 O C:HIS241 4.1 34.1 1.0 ND1 C:HIS59 4.2 27.9 1.0 OE2 T:GLU304 4.3 47.6 1.0 NE2 C:HIS167 4.4 28.1 1.0 CG C:HIS59 4.4 28.3 1.0 CE1 C:HIS167 4.4 27.2 1.0 OD1 C:ASN117 4.4 30.3 1.0 OH C:TYR265 4.4 26.4 1.0 NE2 C:HIS118 4.5 32.7 1.0 CA C:HIS241 4.5 32.7 1.0 C C:HIS241 4.6 33.7 1.0 CE1 C:PHE260 4.7 29.9 1.0 ND1 C:HIS241 4.9 32.9 1.0 CG C:HIS118 5.0 31.3 1.0

V.Stanevich, L.Jiang, K.A.Satyshur, Y.Li, P.D.Jeffrey, Z.Li, P.Menden, M.F.Semmelhack, Y.Xing. The Structural Basis For Tight Control of PP2A Methylation and Function By Lcmt-1. Mol.Cell V. 41 331 2011.
ISSN: ISSN 1097-2765
PubMed: 21292165
DOI: 10.1016/J.MOLCEL.2010.12.030