Atomistry » Manganese » PDB 3n39-3orm » 3nue
Atomistry »
  Manganese »
    PDB 3n39-3orm »
      3nue »

Manganese in PDB 3nue: The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis Complexed with Tryptophan

Enzymatic activity of The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis Complexed with Tryptophan

All present enzymatic activity of The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis Complexed with Tryptophan:
2.5.1.54;

Protein crystallography data

The structure of The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis Complexed with Tryptophan, PDB code: 3nue was solved by E.J.Parker, G.B.Jameson, W.Jiao, C.J.Webby, E.N.Baker, H.M.Baker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 38.69 / 2.50
Space group P 32 2 1
Cell size a, b, c (Å), α, β, γ (°) 204.712, 204.712, 66.264, 90.00, 90.00, 120.00
R / Rfree (%) 18.9 / 22.8

Other elements in 3nue:

The structure of The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis Complexed with Tryptophan also contains other interesting chemical elements:

Chlorine (Cl) 1 atom

Manganese Binding Sites:

The binding sites of Manganese atom in the The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis Complexed with Tryptophan (pdb code 3nue). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis Complexed with Tryptophan, PDB code: 3nue:
Jump to Manganese binding site number: 1; 2;

Manganese binding site 1 out of 2 in 3nue

Go back to Manganese Binding Sites List in 3nue
Manganese binding site 1 out of 2 in the The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis Complexed with Tryptophan


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis Complexed with Tryptophan within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mn463

b:48.7
occ:0.75
 OE1 A:GLU411 2.0 50.0 1.0
OD2 A:ASP441 2.7 64.5 1.0
NE2 A:HIS369 2.8 51.8 1.0
SG A:CYS87 2.8 38.6 1.0
CD A:GLU411 2.8 45.5 1.0
OE2 A:GLU411 3.0 48.2 1.0
CD2 A:HIS369 3.2 49.5 1.0
O A:HOH9025 3.5 36.1 1.0
CG A:ASP441 3.7 63.2 1.0
CB A:CYS87 3.9 29.3 1.0
CE1 A:HIS369 4.0 45.8 1.0
O A:HOH9022 4.1 27.1 1.0
CB A:ASP441 4.2 60.3 1.0
SG A:CYS440 4.2 58.0 1.0
CG A:GLU411 4.3 40.0 1.0
NH2 A:ARG126 4.3 18.9 1.0
NH2 A:ARG382 4.3 68.8 1.0
CA A:CYS87 4.4 26.6 1.0
CG A:HIS369 4.5 47.9 1.0
O A:CYS87 4.6 26.2 1.0
OD1 A:ASP441 4.7 68.2 1.0
C A:CYS87 4.9 25.4 1.0
ND1 A:HIS369 4.9 46.2 1.0
NH1 A:ARG382 4.9 65.4 1.0
CZ A:ARG126 4.9 22.8 1.0
NH1 A:ARG126 5.0 26.2 1.0

Manganese binding site 2 out of 2 in 3nue

Go back to Manganese Binding Sites List in 3nue
Manganese binding site 2 out of 2 in the The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis Complexed with Tryptophan


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis Complexed with Tryptophan within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mn466

b:55.9
occ:0.75
 OE1 B:GLU411 2.1 47.7 1.0
NE2 B:HIS369 2.8 47.8 1.0
CD B:GLU411 2.9 43.0 1.0
OD2 B:ASP441 2.9 51.2 1.0
CD2 B:HIS369 3.0 47.1 1.0
OE2 B:GLU411 3.0 45.8 1.0
SG B:CYS87 3.1 36.4 1.0
CG B:ASP441 3.9 53.3 1.0
NH2 B:ARG382 4.1 65.6 1.0
CE1 B:HIS369 4.1 40.4 1.0
O B:HOH9036 4.2 29.8 1.0
CG B:HIS369 4.3 44.2 1.0
CG B:GLU411 4.3 38.6 1.0
CB B:CYS87 4.4 28.2 1.0
CB B:ASP441 4.4 55.1 1.0
NH2 B:ARG126 4.5 20.7 1.0
NH1 B:ARG382 4.7 62.7 1.0
SG B:CYS440 4.8 54.2 1.0
OD1 B:ASP441 4.8 53.0 1.0
ND1 B:HIS369 4.8 42.4 1.0
CA B:CYS87 4.9 25.2 1.0
CZ B:ARG382 4.9 65.0 1.0
O4 B:PO4463 5.0 26.5 1.0

Reference:

C.J.Webby, W.Jiao, R.D.Hutton, N.J.Blackmore, H.M.Baker, E.N.Baker, G.B.Jameson, E.J.Parker. Synergistic Allostery, A Sophisticated Regulatory Network For the Control of Aromatic Amino Acid Biosynthesis in Mycobacterium Tuberculosis J.Biol.Chem. V. 285 30567 2010.
ISSN: ISSN 0021-9258
PubMed: 20667835
DOI: 10.1074/JBC.M110.111856
Page generated: Tue Dec 15 04:13:11 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy