Manganese in PDB 3mfu: Cask-4M Cam Kinase Domain, Amppnp-MN2+

All present enzymatic activity of Cask-4M Cam Kinase Domain, Amppnp-MN2+:
2.7.11.1;

The structure of Cask-4M Cam Kinase Domain, Amppnp-MN2+, PDB code: 3mfu was solved by M.C.Wahl, K.Mukherjee, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.65 / 2.30
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	58.900, 62.005, 100.608, 90.00, 90.00, 90.00
R / Rfree (%)	17.9 / 23.4

The binding sites of Manganese atom in the Cask-4M Cam Kinase Domain, Amppnp-MN2+ (pdb code 3mfu). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Cask-4M Cam Kinase Domain, Amppnp-MN2+, PDB code: 3mfu:

Manganese binding site 1 out of 1 in the Cask-4M Cam Kinase Domain, Amppnp-MN2+


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Cask-4M Cam Kinase Domain, Amppnp-MN2+ within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn600 b:94.9 occ:1.00 OD2 A:ASP162 2.3 42.4 1.0 O1B A:ANP500 2.6 72.2 1.0 O3A A:ANP500 2.6 68.3 1.0 OD1 A:ASN146 2.6 41.2 1.0 PB A:ANP500 3.2 72.1 1.0 O A:HOH338 3.2 40.6 1.0 CG A:ASP162 3.2 39.7 1.0 O A:HOH511 3.2 54.8 1.0 CB A:ASP162 3.6 37.3 1.0 O2A A:ANP500 3.7 62.1 1.0 CG A:ASN146 3.7 39.5 1.0 PA A:ANP500 3.8 62.4 1.0 O A:HOH428 3.9 49.5 1.0 O3G A:ANP500 4.0 79.0 1.0 ND2 A:ASN146 4.2 36.6 1.0 O2B A:ANP500 4.2 70.0 1.0 OD1 A:ASP162 4.3 40.8 1.0 N3B A:ANP500 4.5 75.6 1.0 O5' A:ANP500 4.6 59.4 1.0 PG A:ANP500 4.7 80.7 1.0 CE A:LYS143 4.8 39.3 1.0 O1G A:ANP500 4.9 79.9 1.0 O1A A:ANP500 4.9 63.8 1.0 OD2 A:ASP141 4.9 43.5 1.0 CB A:GLU145 5.0 39.8 1.0 O A:HOH339 5.0 47.5 1.0 CB A:ASN146 5.0 39.2 1.0 O A:HOH426 5.0 39.6 1.0

K.Mukherjee, M.Sharma, R.Jahn, M.C.Wahl, T.C.Sudhof. Evolution of Cask Into A MG2+-Sensitive Kinase. Sci.Signal. V. 3 RA33 2010.
ISSN: ESSN 1937-9145
PubMed: 20424264
DOI: 10.1126/SCISIGNAL.2000800