Manganese in PDB 3idc: Crystal Structure of (102-265)Riib:C Holoenzyme of Camp-Dependent Protein Kinase

All present enzymatic activity of Crystal Structure of (102-265)Riib:C Holoenzyme of Camp-Dependent Protein Kinase:
2.7.11.11;

The structure of Crystal Structure of (102-265)Riib:C Holoenzyme of Camp-Dependent Protein Kinase, PDB code: 3idc was solved by S.H.J.Brown, J.Wu, C.Kim, K.Alberto, S.S.Taylor, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.70
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	179.272, 67.434, 47.325, 90.00, 99.51, 90.00
R / Rfree (%)	24.1 / 31.9

The binding sites of Manganese atom in the Crystal Structure of (102-265)Riib:C Holoenzyme of Camp-Dependent Protein Kinase (pdb code 3idc). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Crystal Structure of (102-265)Riib:C Holoenzyme of Camp-Dependent Protein Kinase, PDB code: 3idc:
Jump to Manganese binding site number: 1; 2;

Manganese binding site 1 out of 2 in the Crystal Structure of (102-265)Riib:C Holoenzyme of Camp-Dependent Protein Kinase


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Crystal Structure of (102-265)Riib:C Holoenzyme of Camp-Dependent Protein Kinase within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn401 b:38.3 occ:1.00 O2G A:ANP450 1.5 52.2 1.0 O2A A:ANP450 2.2 47.8 1.0 OD1 A:ASN171 2.4 45.3 1.0 OD1 A:ASP184 2.6 27.5 1.0 CG A:ASN171 3.0 46.9 1.0 ND2 A:ASN171 3.0 44.0 1.0 PG A:ANP450 3.0 54.3 1.0 NZ A:LYS168 3.6 37.3 1.0 CE A:LYS168 3.6 36.3 1.0 PA A:ANP450 3.6 50.2 1.0 CG A:ASP184 3.6 28.5 1.0 O2B A:ANP450 3.7 57.9 1.0 O1G A:ANP450 3.7 55.4 1.0 O3G A:ANP450 3.8 50.1 1.0 N3B A:ANP450 3.9 54.8 1.0 CB A:ASP184 4.1 31.3 1.0 PB A:ANP450 4.1 54.6 1.0 O3A A:ANP450 4.1 52.8 1.0 O3' A:ANP450 4.2 46.2 1.0 OD2 A:ASP166 4.3 51.8 1.0 MN A:MN402 4.3 40.6 1.0 O1A A:ANP450 4.4 46.3 1.0 CB A:ASN171 4.4 46.3 1.0 O5' A:ANP450 4.6 50.8 1.0 OD2 A:ASP184 4.7 25.4 1.0 C5' A:ANP450 4.8 48.8 1.0 C3' A:ANP450 4.8 48.6 1.0 CA A:ASN171 4.9 46.8 1.0

Manganese binding site 2 out of 2 in the Crystal Structure of (102-265)Riib:C Holoenzyme of Camp-Dependent Protein Kinase


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Crystal Structure of (102-265)Riib:C Holoenzyme of Camp-Dependent Protein Kinase within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn402 b:40.6 occ:1.00 O1G A:ANP450 2.1 55.4 1.0 O2B A:ANP450 2.1 57.9 1.0 OD1 A:ASP184 2.4 27.5 1.0 OD2 A:ASP184 2.6 25.4 1.0 CG A:ASP184 2.8 28.5 1.0 PG A:ANP450 3.2 54.3 1.0 PB A:ANP450 3.3 54.6 1.0 O2G A:ANP450 3.5 52.2 1.0 N3B A:ANP450 3.7 54.8 1.0 OG B:SER112 3.9 42.2 1.0 O1B A:ANP450 3.9 55.3 1.0 NZ A:LYS72 4.1 56.5 1.0 MN A:MN401 4.3 38.3 1.0 CB A:ASP184 4.4 31.3 1.0 CB B:SER112 4.4 46.2 1.0 OD2 A:ASP166 4.4 51.8 1.0 O3G A:ANP450 4.5 50.1 1.0 CA A:GLY186 4.5 43.8 1.0 O2A A:ANP450 4.5 47.8 1.0 O3A A:ANP450 4.6 52.8 1.0 CE2 A:PHE187 4.6 51.3 1.0 O1A A:ANP450 4.7 46.3 1.0 CZ A:PHE187 4.7 50.5 1.0 N A:GLY186 4.8 42.3 1.0 PA A:ANP450 4.8 50.2 1.0

S.H.Brown, J.Wu, C.Kim, K.Alberto, S.S.Taylor. Novel Isoform-Specific Interfaces Revealed By Pka Riibeta Holoenzyme Structures. J.Mol.Biol. V. 393 1070 2009.
ISSN: ISSN 0022-2836
PubMed: 19748511
DOI: 10.1016/J.JMB.2009.09.014