Manganese in PDB 3idb: Crystal Structure of (108-268)Riib:C Holoenzyme of Camp-Dependent Protein Kinase

All present enzymatic activity of Crystal Structure of (108-268)Riib:C Holoenzyme of Camp-Dependent Protein Kinase:
2.7.11.11;

The structure of Crystal Structure of (108-268)Riib:C Holoenzyme of Camp-Dependent Protein Kinase, PDB code: 3idb was solved by S.H.J.Brown, J.Wu, C.Kim, K.Alberto, S.S.Taylor, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.62
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	173.321, 65.733, 47.155, 90.00, 99.95, 90.00
R / Rfree (%)	20.6 / 23

The binding sites of Manganese atom in the Crystal Structure of (108-268)Riib:C Holoenzyme of Camp-Dependent Protein Kinase (pdb code 3idb). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Crystal Structure of (108-268)Riib:C Holoenzyme of Camp-Dependent Protein Kinase, PDB code: 3idb:
Jump to Manganese binding site number: 1; 2;

Manganese binding site 1 out of 2 in the Crystal Structure of (108-268)Riib:C Holoenzyme of Camp-Dependent Protein Kinase


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Crystal Structure of (108-268)Riib:C Holoenzyme of Camp-Dependent Protein Kinase within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn401 b:12.7 occ:1.00 OD1 A:ASN171 2.0 11.7 1.0 O2A A:ANP450 2.1 14.4 1.0 OD2 A:ASP184 2.1 10.0 1.0 O2G A:ANP450 2.2 14.9 1.0 O A:HOH500 2.3 12.9 1.0 N3B A:ANP450 2.8 13.6 1.0 PG A:ANP450 3.0 15.4 1.0 CG A:ASN171 3.1 12.2 1.0 CG A:ASP184 3.1 13.0 1.0 PA A:ANP450 3.4 14.7 1.0 ND2 A:ASN171 3.5 9.3 1.0 CB A:ASP184 3.5 11.3 1.0 PB A:ANP450 3.7 14.3 1.0 O2B A:ANP450 3.8 14.7 1.0 O1G A:ANP450 3.8 16.6 1.0 O3A A:ANP450 3.9 13.8 1.0 MN A:MN402 4.0 12.8 1.0 CE A:LYS168 4.0 11.3 1.0 O1A A:ANP450 4.1 15.2 1.0 OD1 A:ASP184 4.2 12.2 1.0 O B:HOH504 4.2 22.8 1.0 O3G A:ANP450 4.2 15.0 1.0 NZ A:LYS168 4.3 14.7 1.0 O3' A:ANP450 4.4 14.8 1.0 OD2 A:ASP166 4.4 14.1 1.0 CB A:ASN171 4.4 10.4 1.0 O B:HOH505 4.5 16.3 1.0 O5' A:ANP450 4.6 14.5 1.0 CA A:ASN171 4.8 10.3 1.0 O A:GLU170 4.8 11.9 1.0 C5' A:ANP450 4.8 15.0 1.0 O A:HOH502 4.9 13.2 1.0 C3' A:ANP450 4.9 15.4 1.0

Manganese binding site 2 out of 2 in the Crystal Structure of (108-268)Riib:C Holoenzyme of Camp-Dependent Protein Kinase


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Crystal Structure of (108-268)Riib:C Holoenzyme of Camp-Dependent Protein Kinase within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn402 b:12.8 occ:1.00 O1G A:ANP450 2.1 16.6 1.0 O A:HOH501 2.1 14.2 1.0 O2B A:ANP450 2.1 14.7 1.0 O A:HOH502 2.2 13.2 1.0 OD1 A:ASP184 2.3 12.2 1.0 OD2 A:ASP184 2.4 10.0 1.0 CG A:ASP184 2.7 13.0 1.0 PG A:ANP450 3.2 15.4 1.0 PB A:ANP450 3.3 14.3 1.0 N3B A:ANP450 3.6 13.6 1.0 O2G A:ANP450 3.6 14.9 1.0 MN A:MN401 4.0 12.7 1.0 OD2 A:ASP166 4.1 14.1 1.0 O1B A:ANP450 4.1 17.7 1.0 OG B:SER112 4.2 14.0 1.0 O A:HOH574 4.2 46.0 1.0 O A:HOH503 4.2 25.4 1.0 CB A:ASP184 4.2 11.3 1.0 CA A:GLY186 4.3 13.1 1.0 NZ A:LYS72 4.3 15.6 1.0 O3G A:ANP450 4.5 15.0 1.0 O3A A:ANP450 4.5 13.8 1.0 N A:GLY186 4.6 11.8 1.0 O A:HOH824 4.6 46.6 1.0 O1A A:ANP450 4.7 15.2 1.0 O2A A:ANP450 4.7 14.4 1.0 CB B:SER112 4.7 14.0 1.0 PA A:ANP450 4.8 14.7 1.0 CA A:ASP184 5.0 11.1 1.0

S.H.Brown, J.Wu, C.Kim, K.Alberto, S.S.Taylor. Novel Isoform-Specific Interfaces Revealed By Pka Riibeta Holoenzyme Structures. J.Mol.Biol. V. 393 1070 2009.
ISSN: ISSN 0022-2836
PubMed: 19748511
DOI: 10.1016/J.JMB.2009.09.014