Manganese in PDB 3fhi: Crystal Structure of A Complex Between the Catalytic and Regulatory (Ri{Alpha}) Subunits of Pka

All present enzymatic activity of Crystal Structure of A Complex Between the Catalytic and Regulatory (Ri{Alpha}) Subunits of Pka:
2.7.11.11;

The structure of Crystal Structure of A Complex Between the Catalytic and Regulatory (Ri{Alpha}) Subunits of Pka, PDB code: 3fhi was solved by C.Kim, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	54.453, 93.017, 122.043, 90.00, 90.00, 90.00
R / Rfree (%)	19.8 / 22.6

The binding sites of Manganese atom in the Crystal Structure of A Complex Between the Catalytic and Regulatory (Ri{Alpha}) Subunits of Pka (pdb code 3fhi). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Crystal Structure of A Complex Between the Catalytic and Regulatory (Ri{Alpha}) Subunits of Pka, PDB code: 3fhi:
Jump to Manganese binding site number: 1; 2;

Manganese binding site 1 out of 2 in the Crystal Structure of A Complex Between the Catalytic and Regulatory (Ri{Alpha}) Subunits of Pka


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Crystal Structure of A Complex Between the Catalytic and Regulatory (Ri{Alpha}) Subunits of Pka within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn401 b:2.0 occ:1.00 OD1 A:ASP184 1.8 43.6 1.0 O A:HOH416 1.9 33.9 1.0 OD1 A:ASN171 2.0 44.4 1.0 O2A A:ANP400 2.1 26.5 1.0 O2G A:ANP400 2.2 24.8 1.0 N3B A:ANP400 2.8 21.1 1.0 CG A:ASP184 2.9 44.7 1.0 CG A:ASN171 3.0 42.7 1.0 PG A:ANP400 3.0 21.3 1.0 ND2 A:ASN171 3.4 40.2 1.0 PA A:ANP400 3.4 24.4 1.0 CB A:ASP184 3.5 43.9 1.0 PB A:ANP400 3.7 20.3 1.0 O1G A:ANP400 3.8 17.4 1.0 O3A A:ANP400 3.8 23.8 1.0 OD2 A:ASP184 3.9 43.1 1.0 MN A:MN402 4.0 2.0 1.0 CE A:LYS168 4.1 43.6 1.0 O2B A:ANP400 4.1 22.1 1.0 O3G A:ANP400 4.3 14.8 1.0 NZ A:LYS168 4.3 43.0 1.0 OD1 A:ASP166 4.3 47.0 1.0 O3' A:ANP400 4.4 24.4 1.0 CB A:ASN171 4.4 41.9 1.0 O1A A:ANP400 4.4 26.2 1.0 O5' A:ANP400 4.5 23.0 1.0 C5' A:ANP400 4.6 22.4 1.0 C3' A:ANP400 4.8 24.8 1.0 CA A:ASN171 4.8 42.1 1.0 O A:GLU170 4.9 41.3 1.0 O A:HOH497 4.9 53.6 1.0 CA A:ASP184 4.9 44.0 1.0

Manganese binding site 2 out of 2 in the Crystal Structure of A Complex Between the Catalytic and Regulatory (Ri{Alpha}) Subunits of Pka


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Crystal Structure of A Complex Between the Catalytic and Regulatory (Ri{Alpha}) Subunits of Pka within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn402 b:2.0 occ:1.00 O1G A:ANP400 1.9 17.4 1.0 OD2 A:ASP184 2.1 43.1 1.0 O A:HOH372 2.2 32.7 1.0 O2B A:ANP400 2.2 22.1 1.0 O A:HOH356 2.3 37.7 1.0 OD1 A:ASP184 2.7 43.6 1.0 CG A:ASP184 2.7 44.7 1.0 PG A:ANP400 3.2 21.3 1.0 PB A:ANP400 3.3 20.3 1.0 N3B A:ANP400 3.6 21.1 1.0 O2G A:ANP400 3.7 24.8 1.0 MN A:MN401 4.0 2.0 1.0 CD2 A:PHE54 4.0 39.3 1.0 OD1 A:ASP166 4.0 47.0 1.0 CB A:ASP184 4.2 43.9 1.0 O A:HOH366 4.3 40.7 1.0 NZ A:LYS72 4.3 37.9 1.0 CA A:GLY186 4.3 43.5 1.0 O1B A:ANP400 4.4 21.0 1.0 CE2 A:PHE54 4.5 39.2 1.0 O3A A:ANP400 4.5 23.8 1.0 O3G A:ANP400 4.5 14.8 1.0 N A:GLY186 4.6 44.0 1.0 O2A A:ANP400 4.7 26.5 1.0 CB B:ALA97 4.7 34.8 1.0 PA A:ANP400 4.8 24.4 1.0 CA A:ASP184 4.9 44.0 1.0 O1A A:ANP400 4.9 26.2 1.0 O A:HOH452 5.0 40.9 1.0 CZ A:PHE187 5.0 42.6 1.0

C.Kim, N.H.Xuong, S.S.Taylor. Crystal Structure of A Complex Between the Catalytic and Regulatory (Rialpha) Subunits of Pka. Science V. 307 690 2005.
ISSN: ISSN 0036-8075
PubMed: 15692043
DOI: 10.1126/SCIENCE.1104607