Atomistry » Manganese » PDB 2who-2ypp » 2whx
Atomistry »
  Manganese »
    PDB 2who-2ypp »
      2whx »

Manganese in PDB 2whx: A Second Conformation of the NS3 Protease-Helicase From Dengue Virus

Enzymatic activity of A Second Conformation of the NS3 Protease-Helicase From Dengue Virus

All present enzymatic activity of A Second Conformation of the NS3 Protease-Helicase From Dengue Virus:
3.4.21.91; 3.6.1.15;

Protein crystallography data

The structure of A Second Conformation of the NS3 Protease-Helicase From Dengue Virus, PDB code: 2whx was solved by D.Luo, J.Lescar, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.87 / 2.20
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 52.420, 87.720, 75.779, 90.00, 92.90, 90.00
R / Rfree (%) 22.806 / 27.233

Other elements in 2whx:

The structure of A Second Conformation of the NS3 Protease-Helicase From Dengue Virus also contains other interesting chemical elements:

Chlorine (Cl) 2 atoms

Manganese Binding Sites:

The binding sites of Manganese atom in the A Second Conformation of the NS3 Protease-Helicase From Dengue Virus (pdb code 2whx). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the A Second Conformation of the NS3 Protease-Helicase From Dengue Virus, PDB code: 2whx:

Manganese binding site 1 out of 1 in 2whx

Go back to Manganese Binding Sites List in 2whx
Manganese binding site 1 out of 1 in the A Second Conformation of the NS3 Protease-Helicase From Dengue Virus


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of A Second Conformation of the NS3 Protease-Helicase From Dengue Virus within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mn1620

b:25.1
occ:1.00
 O A:HOH2135 2.1 19.9 1.0
OE2 A:GLU285 2.2 22.4 1.0
O A:HOH2136 2.2 16.5 1.0
O2B A:ADP1619 2.2 26.4 1.0
OG1 A:THR200 2.3 17.6 1.0
O A:HOH2137 2.5 14.2 1.0
CD A:GLU285 3.1 21.6 1.0
OE1 A:GLU285 3.3 22.6 1.0
CB A:THR200 3.4 16.9 1.0
PB A:ADP1619 3.4 27.8 1.0
O1B A:ADP1619 3.6 26.1 1.0
O1A A:ADP1619 3.9 29.4 1.0
OD2 A:ASP284 4.0 16.9 1.0
O A:HOH2031 4.0 21.2 1.0
N A:THR200 4.2 17.1 1.0
OD1 A:ASP284 4.2 15.1 1.0
O A:HOH2080 4.3 14.0 1.0
CA A:THR200 4.4 17.3 1.0
O3A A:ADP1619 4.4 27.8 1.0
CG2 A:THR200 4.4 17.1 1.0
O A:HOH2094 4.4 21.6 1.0
CG A:ASP284 4.5 16.5 1.0
CG A:GLU285 4.5 20.2 1.0
O3B A:ADP1619 4.5 26.3 1.0
PA A:ADP1619 4.6 29.6 1.0
O A:HOH2079 4.7 18.3 1.0
NZ A:LYS199 4.9 17.3 1.0
CB A:LYS199 4.9 17.7 1.0
O2A A:ADP1619 4.9 29.0 1.0
CL A:CL1621 4.9 37.2 1.0
NH2 A:ARG463 5.0 19.0 1.0
CA A:GLY414 5.0 19.3 1.0

Reference:

D.Luo, N.Wei, D.N.Doan, P.N.Paradkar, Y.Chong, A.D.Davidson, M.Kotaka, J.Lescar, S.G.Vasudevan. Flexibility Between the Protease and Helicase Domains of the Dengue Virus NS3 Protein Conferred By the Linker Region and Its Functional Implications. J.Biol.Chem. V. 285 18817 2010.
ISSN: ISSN 0021-9258
PubMed: 20375022
DOI: 10.1074/JBC.M109.090936
Page generated: Sat Oct 5 15:23:52 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy