Manganese in PDB 2o1h: Naturally Occurring Mutation of Humna Abo(H) Galactosyltransferase in Complex with Udp: Gtb/M214T_UDP

The structure of Naturally Occurring Mutation of Humna Abo(H) Galactosyltransferase in Complex with Udp: Gtb/M214T_UDP, PDB code: 2o1h was solved by J.A.Letts, S.N.Borisova, S.V.Evans, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.67
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	52.600, 149.490, 79.240, 90.00, 90.00, 90.00
R / Rfree (%)	17.6 / 22.2

The structure of Naturally Occurring Mutation of Humna Abo(H) Galactosyltransferase in Complex with Udp: Gtb/M214T_UDP also contains other interesting chemical elements:

Mercury

(Hg)

5 atoms

The binding sites of Manganese atom in the Naturally Occurring Mutation of Humna Abo(H) Galactosyltransferase in Complex with Udp: Gtb/M214T_UDP (pdb code 2o1h). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Naturally Occurring Mutation of Humna Abo(H) Galactosyltransferase in Complex with Udp: Gtb/M214T_UDP, PDB code: 2o1h:

Manganese binding site 1 out of 1 in the Naturally Occurring Mutation of Humna Abo(H) Galactosyltransferase in Complex with Udp: Gtb/M214T_UDP


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Naturally Occurring Mutation of Humna Abo(H) Galactosyltransferase in Complex with Udp: Gtb/M214T_UDP within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn450 b:34.1 occ:0.50 O1A A:UDP500 1.9 52.8 1.0 O1B A:UDP500 2.1 52.8 1.0 O A:HOH641 2.1 40.2 1.0 OD2 A:ASP213 2.4 22.5 1.0 OD2 A:ASP211 2.7 27.4 1.0 OD1 A:ASP213 2.8 28.5 1.0 CG A:ASP213 2.9 21.7 1.0 PA A:UDP500 3.2 55.8 1.0 PB A:UDP500 3.3 57.4 1.0 CG A:ASP211 3.5 19.6 1.0 CB A:ASP211 3.6 18.0 1.0 O3A A:UDP500 3.6 56.2 1.0 O3' A:UDP500 3.7 38.8 1.0 O2A A:UDP500 3.8 60.0 1.0 O A:HOH695 4.0 46.3 1.0 O3B A:UDP500 4.0 57.1 1.0 O2B A:UDP500 4.3 58.7 1.0 O5' A:UDP500 4.4 50.6 1.0 CB A:ASP213 4.4 19.9 1.0 C3' A:UDP500 4.5 41.7 1.0 C5' A:UDP500 4.6 44.4 1.0 OD1 A:ASP211 4.6 22.3 1.0 O A:ASP213 4.8 18.9 1.0 C4' A:UDP500 4.9 43.5 1.0

M.Persson, J.A.Letts, B.Hosseini-Maaf, S.N.Borisova, M.M.Palcic, S.V.Evans, M.L.Olsson. Structural Effects of Naturally Occurring Human Blood Group B Galactosyltransferase Mutations Adjacent to the Dxd Motif. J.Biol.Chem. V. 282 9564 2007.
ISSN: ISSN 0021-9258
PubMed: 17259183
DOI: 10.1074/JBC.M610998200