Manganese in PDB 2lgs: Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine

All present enzymatic activity of Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine:
6.3.1.2;

The structure of Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine, PDB code: 2lgs was solved by S.-H.Liaw, D.Eisenberg, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	8.00 / 2.80
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	235.500, 134.500, 200.100, 90.00, 102.80, 90.00
R / Rfree (%)	23.5 / n/a

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 24;

Binding sites:

The binding sites of Manganese atom in the Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine (pdb code 2lgs). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 24 binding sites of Manganese where determined in the Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine, PDB code: 2lgs:
Jump to Manganese binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Manganese binding site 1 out of 24 in the Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn469 b:25.7 occ:1.00 OE1 A:GLU220 2.1 38.3 1.0 OE2 A:GLU131 2.2 25.9 1.0 OE2 A:GLU212 2.3 35.7 1.0 CD A:GLU220 3.0 38.3 1.0 CD A:GLU212 3.2 35.7 1.0 CD A:GLU131 3.2 25.9 1.0 OE2 A:GLU220 3.3 38.3 1.0 OE2 A:GLU471 3.3 48.6 1.0 CG A:GLU131 3.8 25.9 1.0 CG A:GLU212 3.8 35.7 1.0 CG A:GLU471 3.9 36.6 1.0 CD A:GLU471 4.0 41.2 1.0 OE1 A:GLU212 4.0 35.7 1.0 OE1 A:GLU131 4.2 25.9 1.0 CG A:GLU220 4.3 38.3 1.0 CB A:GLU471 4.5 31.8 1.0 CE1 A:HIS210 4.7 18.1 1.0 CB A:GLU220 4.8 38.3 1.0 N A:GLU471 4.9 32.2 1.0

Manganese binding site 2 out of 24 in the Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn470 b:25.7 occ:1.00 OE1 A:GLU129 2.2 35.8 1.0 OE2 A:GLU357 2.4 29.3 1.0 OE2 A:GLU129 2.9 35.8 1.0 CD A:GLU129 2.9 35.8 1.0 CD A:GLU357 3.1 29.3 1.0 OE1 A:GLU357 3.1 29.3 1.0 ND1 A:HIS269 3.1 42.1 1.0 CE1 A:HIS269 3.8 42.1 1.0 NH2 A:ARG359 3.9 59.4 1.0 CG A:HIS269 3.9 42.1 1.0 NE A:ARG344 3.9 71.2 1.0 CB A:HIS269 4.4 42.1 1.0 CZ A:ARG359 4.4 59.4 1.0 CG A:GLU129 4.5 35.8 1.0 NH2 A:ARG344 4.5 71.2 1.0 CG A:GLU357 4.5 29.3 1.0 NE A:ARG359 4.5 59.4 1.0 CZ A:ARG344 4.5 71.2 1.0 NE2 A:HIS271 4.5 32.1 1.0 CD A:ARG344 4.7 71.2 1.0 NE2 A:HIS269 4.8 42.1 1.0 OE1 A:GLU471 4.9 57.5 1.0 CD2 A:HIS269 4.9 42.1 1.0

Manganese binding site 3 out of 24 in the Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 3 of Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine within 5.0Å range: probe atom residue distance (Å) B Occ B:Mn471 b:25.7 occ:1.00 OE1 B:GLU220 2.1 38.3 1.0 OE2 B:GLU131 2.2 25.9 1.0 OE2 B:GLU212 2.3 35.7 1.0 CD B:GLU220 3.0 38.3 1.0 CD B:GLU212 3.2 35.7 1.0 CD B:GLU131 3.2 25.9 1.0 OE2 B:GLU220 3.3 38.3 1.0 OE2 B:GLU473 3.3 48.6 1.0 CG B:GLU131 3.8 25.9 1.0 CG B:GLU212 3.8 35.7 1.0 CG B:GLU473 3.9 36.6 1.0 CD B:GLU473 4.0 41.2 1.0 OE1 B:GLU212 4.0 35.7 1.0 OE1 B:GLU131 4.2 25.9 1.0 CG B:GLU220 4.3 38.3 1.0 CB B:GLU473 4.5 31.8 1.0 CE1 B:HIS210 4.7 18.1 1.0 CB B:GLU220 4.8 38.3 1.0 N B:GLU473 4.9 32.2 1.0

Manganese binding site 4 out of 24 in the Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 4 of Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine within 5.0Å range: probe atom residue distance (Å) B Occ B:Mn472 b:25.7 occ:1.00 OE1 B:GLU129 2.2 35.8 1.0 OE2 B:GLU357 2.4 29.3 1.0 OE2 B:GLU129 2.9 35.8 1.0 CD B:GLU129 2.9 35.8 1.0 CD B:GLU357 3.1 29.3 1.0 OE1 B:GLU357 3.1 29.3 1.0 ND1 B:HIS269 3.1 42.1 1.0 CE1 B:HIS269 3.8 42.1 1.0 NH2 B:ARG359 3.9 59.4 1.0 CG B:HIS269 3.9 42.1 1.0 NE B:ARG344 3.9 71.2 1.0 CB B:HIS269 4.4 42.1 1.0 CZ B:ARG359 4.4 59.4 1.0 CG B:GLU129 4.5 35.8 1.0 NH2 B:ARG344 4.5 71.2 1.0 CG B:GLU357 4.5 29.3 1.0 NE B:ARG359 4.5 59.4 1.0 CZ B:ARG344 4.5 71.2 1.0 NE2 B:HIS271 4.5 32.1 1.0 CD B:ARG344 4.7 71.2 1.0 NE2 B:HIS269 4.8 42.1 1.0 OE1 B:GLU473 4.9 57.5 1.0 CD2 B:HIS269 4.9 42.1 1.0

Manganese binding site 5 out of 24 in the Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 5 of Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine within 5.0Å range: probe atom residue distance (Å) B Occ C:Mn473 b:25.7 occ:1.00 OE1 C:GLU220 2.1 38.3 1.0 OE2 C:GLU131 2.2 25.9 1.0 OE2 C:GLU212 2.3 35.7 1.0 CD C:GLU220 3.0 38.3 1.0 CD C:GLU212 3.2 35.7 1.0 CD C:GLU131 3.2 25.9 1.0 OE2 C:GLU220 3.3 38.3 1.0 OE2 C:GLU471 3.3 48.6 1.0 CG C:GLU131 3.8 25.9 1.0 CG C:GLU212 3.8 35.7 1.0 CG C:GLU471 3.9 36.6 1.0 CD C:GLU471 4.0 41.2 1.0 OE1 C:GLU212 4.0 35.7 1.0 OE1 C:GLU131 4.2 25.9 1.0 CG C:GLU220 4.3 38.3 1.0 CB C:GLU471 4.5 31.8 1.0 CE1 C:HIS210 4.7 18.1 1.0 CB C:GLU220 4.8 38.3 1.0 N C:GLU471 4.9 32.2 1.0

Manganese binding site 6 out of 24 in the Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 6 of Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine within 5.0Å range: probe atom residue distance (Å) B Occ C:Mn474 b:25.7 occ:1.00 OE1 C:GLU129 2.2 35.8 1.0 OE2 C:GLU357 2.4 29.3 1.0 OE2 C:GLU129 2.9 35.8 1.0 CD C:GLU129 2.9 35.8 1.0 CD C:GLU357 3.1 29.3 1.0 OE1 C:GLU357 3.1 29.3 1.0 ND1 C:HIS269 3.1 42.1 1.0 CE1 C:HIS269 3.8 42.1 1.0 NH2 C:ARG359 3.9 59.4 1.0 CG C:HIS269 3.9 42.1 1.0 NE C:ARG344 3.9 71.2 1.0 CB C:HIS269 4.4 42.1 1.0 CZ C:ARG359 4.4 59.4 1.0 CG C:GLU129 4.5 35.8 1.0 NH2 C:ARG344 4.5 71.2 1.0 CG C:GLU357 4.5 29.3 1.0 NE C:ARG359 4.5 59.4 1.0 CZ C:ARG344 4.5 71.2 1.0 NE2 C:HIS271 4.5 32.1 1.0 CD C:ARG344 4.7 71.2 1.0 NE2 C:HIS269 4.8 42.1 1.0 OE1 C:GLU471 4.9 57.5 1.0 CD2 C:HIS269 4.9 42.1 1.0

Manganese binding site 7 out of 24 in the Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 7 of Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine within 5.0Å range: probe atom residue distance (Å) B Occ D:Mn475 b:25.7 occ:1.00 OE1 D:GLU220 2.1 38.3 1.0 OE2 D:GLU131 2.2 25.9 1.0 OE2 D:GLU212 2.3 35.7 1.0 CD D:GLU220 3.0 38.3 1.0 CD D:GLU212 3.2 35.7 1.0 CD D:GLU131 3.2 25.9 1.0 OE2 D:GLU220 3.3 38.3 1.0 OE2 D:GLU471 3.3 48.6 1.0 CG D:GLU131 3.8 25.9 1.0 CG D:GLU212 3.8 35.7 1.0 CG D:GLU471 3.9 36.6 1.0 CD D:GLU471 4.0 41.2 1.0 OE1 D:GLU212 4.0 35.7 1.0 OE1 D:GLU131 4.2 25.9 1.0 CG D:GLU220 4.3 38.3 1.0 CB D:GLU471 4.5 31.8 1.0 CE1 D:HIS210 4.7 18.1 1.0 CB D:GLU220 4.8 38.3 1.0 N D:GLU471 4.9 32.2 1.0

Manganese binding site 8 out of 24 in the Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 8 of Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine within 5.0Å range: probe atom residue distance (Å) B Occ D:Mn476 b:25.7 occ:1.00 OE1 D:GLU129 2.2 35.8 1.0 OE2 D:GLU357 2.4 29.3 1.0 OE2 D:GLU129 2.9 35.8 1.0 CD D:GLU129 2.9 35.8 1.0 CD D:GLU357 3.1 29.3 1.0 OE1 D:GLU357 3.1 29.3 1.0 ND1 D:HIS269 3.1 42.1 1.0 CE1 D:HIS269 3.8 42.1 1.0 NH2 D:ARG359 3.9 59.4 1.0 CG D:HIS269 3.9 42.1 1.0 NE D:ARG344 3.9 71.2 1.0 CB D:HIS269 4.4 42.1 1.0 CZ D:ARG359 4.4 59.4 1.0 CG D:GLU129 4.5 35.8 1.0 NH2 D:ARG344 4.5 71.2 1.0 CG D:GLU357 4.5 29.3 1.0 NE D:ARG359 4.5 59.4 1.0 CZ D:ARG344 4.5 71.2 1.0 NE2 D:HIS271 4.5 32.1 1.0 CD D:ARG344 4.7 71.2 1.0 NE2 D:HIS269 4.8 42.1 1.0 OE1 D:GLU471 4.9 57.5 1.0 CD2 D:HIS269 4.9 42.1 1.0

Manganese binding site 9 out of 24 in the Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 9 of Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine within 5.0Å range: probe atom residue distance (Å) B Occ E:Mn477 b:25.7 occ:1.00 OE1 E:GLU220 2.1 38.3 1.0 OE2 E:GLU131 2.2 25.9 1.0 OE2 E:GLU212 2.3 35.7 1.0 CD E:GLU220 3.0 38.3 1.0 CD E:GLU212 3.2 35.7 1.0 CD E:GLU131 3.2 25.9 1.0 OE2 E:GLU220 3.3 38.3 1.0 OE2 E:GLU471 3.3 48.6 1.0 CG E:GLU131 3.8 25.9 1.0 CG E:GLU212 3.8 35.7 1.0 CG E:GLU471 3.9 36.6 1.0 CD E:GLU471 4.0 41.2 1.0 OE1 E:GLU212 4.0 35.7 1.0 OE1 E:GLU131 4.2 25.9 1.0 CG E:GLU220 4.3 38.3 1.0 CB E:GLU471 4.5 31.8 1.0 CE1 E:HIS210 4.7 18.1 1.0 CB E:GLU220 4.8 38.3 1.0 N E:GLU471 4.9 32.2 1.0

Manganese binding site 10 out of 24 in the Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 10 of Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine within 5.0Å range: probe atom residue distance (Å) B Occ E:Mn478 b:25.7 occ:1.00 OE1 E:GLU129 2.2 35.8 1.0 OE2 E:GLU357 2.4 29.3 1.0 OE2 E:GLU129 2.9 35.8 1.0 CD E:GLU129 2.9 35.8 1.0 CD E:GLU357 3.1 29.3 1.0 OE1 E:GLU357 3.1 29.3 1.0 ND1 E:HIS269 3.1 42.1 1.0 CE1 E:HIS269 3.8 42.1 1.0 NH2 E:ARG359 3.9 59.4 1.0 CG E:HIS269 3.9 42.1 1.0 NE E:ARG344 3.9 71.2 1.0 CB E:HIS269 4.4 42.1 1.0 CZ E:ARG359 4.4 59.4 1.0 CG E:GLU129 4.5 35.8 1.0 NH2 E:ARG344 4.5 71.2 1.0 CG E:GLU357 4.5 29.3 1.0 NE E:ARG359 4.5 59.4 1.0 CZ E:ARG344 4.5 71.2 1.0 NE2 E:HIS271 4.5 32.1 1.0 CD E:ARG344 4.7 71.2 1.0 NE2 E:HIS269 4.8 42.1 1.0 OE1 E:GLU471 4.9 57.5 1.0 CD2 E:HIS269 4.9 42.1 1.0

S.H.Liaw, C.Pan, D.Eisenberg. Feedback Inhibition of Fully Unadenylylated Glutamine Synthetase From Salmonella Typhimurium By Glycine, Alanine, and Serine. Proc.Natl.Acad.Sci.Usa V. 90 4996 1993.
ISSN: ISSN 0027-8424
PubMed: 8099447
DOI: 10.1073/PNAS.90.11.4996