Manganese in the structure of Foot and Mouth Disease Virus Rna-Dependent Rna Polymerase in Complex With Uridylylated Vpg Protein (pdb 2f8e)

The binding sites of Manganese atom in the structure of Foot and Mouth Disease Virus Rna-Dependent Rna Polymerase in Complex With Uridylylated Vpg Protein (pdb code 2f8e). This binding sites where shown with 5.0 Angstroms radius around Manganese atom. The 2f8e structure was solved by C.FERRER-ORTA, A.ARIAS, R.PEREZ-LUQUE, C.ESCARMIS, E.DOMINGO, N.VERDAGUER, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 30.0-2.9 Space group P3221 a (A) 94.381 b (A) 94.381 c (A) 99.726 alpha (°) 90.00 beta (°) 90.00 gamma (°) 120.00 Rfactor (%) 23.4 Rfree (%) 28.4 Manganese Binding Sites: Manganese binding site 1 out of 1 in 2f8e Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Manganese in the PDB 2f8e. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Manganese atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: X: Asp338, A: Tyr1003, A: Ala1004, A: Gly1005, A: Glu1008, A: U5p2003, conact list: Atom Atom Distance (A) Mn OD2 X:Asp338 3.61 Mn OD1 X:Asp338 4.52 Mn CG X:Asp338 4.48 Mn O A:Tyr1003 4.89 Mn CE2 A:Tyr1003 4.04 Mn CD2 A:Tyr1003 4.67 Mn CZ A:Tyr1003 4.33 Mn OH A:Tyr1003 4.37 Mn CA A:Ala1004 4.47 Mn N A:Gly1005 4.63 Mn OE1 A:Glu1008 5.00 Mn P A:U5p2003 3.38 Mn O4' A:U5p2003 4.22 Mn C5' A:U5p2003 4.82 Mn O1P A:U5p2003 4.45 Mn O5' A:U5p2003 3.70 Mn O2P A:U5p2003 2.02 interactive model: