Manganese in PDB 2f6k: Crystal Structure of Amidohydrorolase II; Northeast Structural Genomics Target LPR24

All present enzymatic activity of Crystal Structure of Amidohydrorolase II; Northeast Structural Genomics Target LPR24:
4.1.1.45;

The structure of Crystal Structure of Amidohydrorolase II; Northeast Structural Genomics Target LPR24, PDB code: 2f6k was solved by K.Das, R.Xiao, T.Acton, L.Ma, E.Arnold, G.T.Montelione, Northeaststructural Genomics Consortium (Nesg), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.90 / 2.50
Space group	P 43 2 2
Cell size a, b, c (Å), α, β, γ (°)	82.620, 82.620, 240.815, 90.00, 90.00, 90.00
R / Rfree (%)	19.2 / 22.5

The binding sites of Manganese atom in the Crystal Structure of Amidohydrorolase II; Northeast Structural Genomics Target LPR24 (pdb code 2f6k). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Crystal Structure of Amidohydrorolase II; Northeast Structural Genomics Target LPR24, PDB code: 2f6k:
Jump to Manganese binding site number: 1; 2;

Manganese binding site 1 out of 2 in the Crystal Structure of Amidohydrorolase II; Northeast Structural Genomics Target LPR24


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Crystal Structure of Amidohydrorolase II; Northeast Structural Genomics Target LPR24 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn402 b:26.5 occ:1.00 O A:HOH409 2.1 19.8 1.0 NE2 A:HIS154 2.1 36.0 1.0 NE2 A:HIS7 2.1 32.3 1.0 NE2 A:HIS9 2.3 27.1 1.0 O A:HOH459 2.3 34.6 1.0 OD1 A:ASP266 2.4 38.8 1.0 CE1 A:HIS154 3.0 35.8 1.0 CE1 A:HIS7 3.1 28.3 1.0 CD2 A:HIS7 3.1 29.9 1.0 CD2 A:HIS154 3.2 36.2 1.0 CG A:ASP266 3.2 37.7 1.0 CD2 A:HIS9 3.2 28.7 1.0 CE1 A:HIS9 3.2 29.6 1.0 OD2 A:ASP266 3.4 39.4 1.0 ND1 A:HIS154 4.1 33.5 1.0 OG A:SER57 4.1 39.6 1.0 ND1 A:HIS7 4.2 29.0 1.0 CG A:HIS154 4.3 33.1 1.0 CG A:HIS7 4.3 30.6 1.0 ND1 A:HIS9 4.4 28.5 1.0 CG A:HIS9 4.4 26.6 1.0 CB A:ASP266 4.6 35.0 1.0 NE2 A:HIS205 4.6 30.2 1.0 CB A:SER57 4.8 38.0 1.0 CE1 A:HIS205 4.8 28.2 1.0 CA A:ASP266 4.9 33.3 1.0

Manganese binding site 2 out of 2 in the Crystal Structure of Amidohydrorolase II; Northeast Structural Genomics Target LPR24


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Crystal Structure of Amidohydrorolase II; Northeast Structural Genomics Target LPR24 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mn401 b:31.5 occ:1.00 NE2 B:HIS154 2.2 38.2 1.0 O B:HOH456 2.2 38.8 1.0 NE2 B:HIS7 2.2 36.6 1.0 NE2 B:HIS9 2.3 21.8 1.0 OD1 B:ASP266 2.4 40.9 1.0 O B:HOH454 2.5 35.9 1.0 CE1 B:HIS154 3.0 40.2 1.0 CE1 B:HIS9 3.2 21.5 1.0 CD2 B:HIS154 3.2 39.9 1.0 CD2 B:HIS7 3.2 35.7 1.0 CE1 B:HIS7 3.2 34.3 1.0 CG B:ASP266 3.2 42.2 1.0 CD2 B:HIS9 3.3 21.1 1.0 OD2 B:ASP266 3.5 42.3 1.0 OG B:SER57 3.9 37.6 1.0 ND1 B:HIS154 4.2 39.4 1.0 CG B:HIS154 4.3 34.8 1.0 ND1 B:HIS9 4.3 26.8 1.0 ND1 B:HIS7 4.3 35.3 1.0 CG B:HIS7 4.3 35.9 1.0 CG B:HIS9 4.4 26.2 1.0 CB B:ASP266 4.6 38.0 1.0 NE2 B:HIS205 4.6 32.4 1.0 CB B:SER57 4.7 36.2 1.0 CE1 B:HIS205 4.8 34.4 1.0 CA B:ASP266 4.9 34.6 1.0

K.Das, R.Xiao, T.Acton, L.Ma, E.Arnold, G.T.Montelione. Crystal Structure of Acmds From Lactobacillus Plantarum To Be Published.