Manganese in PDB 2bow: Multidrug-Binding Domain of Transcription Activator Bmrr in Complex with A Ligand, Tetraphenylphosphonium

The structure of Multidrug-Binding Domain of Transcription Activator Bmrr in Complex with A Ligand, Tetraphenylphosphonium, PDB code: 2bow was solved by E.E.Zheleznova, P.N.Markham, A.A.Neyfakh, R.G.Brennan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	16.00 / 2.80
Space group	P 62 2 2
Cell size a, b, c (Å), α, β, γ (°)	82.600, 82.600, 104.200, 90.00, 90.00, 120.00
R / Rfree (%)	n/a / 32.6

The binding sites of Manganese atom in the Multidrug-Binding Domain of Transcription Activator Bmrr in Complex with A Ligand, Tetraphenylphosphonium (pdb code 2bow). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Multidrug-Binding Domain of Transcription Activator Bmrr in Complex with A Ligand, Tetraphenylphosphonium, PDB code: 2bow:

Manganese binding site 1 out of 1 in the Multidrug-Binding Domain of Transcription Activator Bmrr in Complex with A Ligand, Tetraphenylphosphonium


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Multidrug-Binding Domain of Transcription Activator Bmrr in Complex with A Ligand, Tetraphenylphosphonium within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn160 b:36.2 occ:0.50 NE2 A:HIS70 1.9 36.4 1.0 OE2 A:GLU19 2.1 52.0 1.0 OE1 A:GLU19 2.2 27.8 1.0 CD A:GLU19 2.5 49.3 1.0 CE1 A:HIS70 2.5 35.2 1.0 CD2 A:HIS70 3.2 38.8 1.0 ND1 A:HIS70 3.8 35.0 1.0 CG A:GLU19 4.0 52.4 1.0 CG A:HIS70 4.1 35.0 1.0 CB A:GLU19 4.9 55.0 1.0

E.E.Zheleznova, P.N.Markham, A.A.Neyfakh, R.G.Brennan. Structural Basis of Multidrug Recognition By Bmrr, A Transcription Activator of A Multidrug Transporter. Cell(Cambridge,Mass.) V. 96 353 1999.
ISSN: ISSN 0092-8674
PubMed: 10025401
DOI: 10.1016/S0092-8674(00)80548-6