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Manganese in PDB 1xnz: Crystal Structure of Mn(II) Form of E. Coli. Methionine Aminopeptidase in Complex with 5-(2-Chlorophenyl)Furan-2- Carboxylic Acid
Enzymatic activity of Crystal Structure of Mn(II) Form of E. Coli. Methionine Aminopeptidase in Complex with 5-(2-Chlorophenyl)Furan-2- Carboxylic Acid
All present enzymatic activity of Crystal Structure of Mn(II) Form of E. Coli. Methionine Aminopeptidase in Complex with 5-(2-Chlorophenyl)Furan-2- Carboxylic Acid:
3.4.11.18;
3.4.11.18;
Protein crystallography data
The structure of Crystal Structure of Mn(II) Form of E. Coli. Methionine Aminopeptidase in Complex with 5-(2-Chlorophenyl)Furan-2- Carboxylic Acid, PDB code: 1xnz
was solved by
Q.-Z.Ye,
S.-X.Xie,
M.Huang,
W.-J.Huang,
J.-P.Lu,
Z.-Q.Ma,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 10.00 / 1.52 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 37.600, 60.300, 49.700, 90.00, 104.80, 90.00 |
| R / Rfree (%) | 21.9 / 25 |
Other elements in 1xnz:
The structure of Crystal Structure of Mn(II) Form of E. Coli. Methionine Aminopeptidase in Complex with 5-(2-Chlorophenyl)Furan-2- Carboxylic Acid also contains other interesting chemical elements:
| Chlorine | (Cl) | 1 atom |
| Sodium | (Na) | 1 atom |
Manganese Binding Sites:
The binding sites of Manganese atom in the Crystal Structure of Mn(II) Form of E. Coli. Methionine Aminopeptidase in Complex with 5-(2-Chlorophenyl)Furan-2- Carboxylic Acid
(pdb code 1xnz). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Crystal Structure of Mn(II) Form of E. Coli. Methionine Aminopeptidase in Complex with 5-(2-Chlorophenyl)Furan-2- Carboxylic Acid, PDB code: 1xnz:
Jump to Manganese binding site number: 1; 2;
In total 2 binding sites of Manganese where determined in the Crystal Structure of Mn(II) Form of E. Coli. Methionine Aminopeptidase in Complex with 5-(2-Chlorophenyl)Furan-2- Carboxylic Acid, PDB code: 1xnz:
Jump to Manganese binding site number: 1; 2;
Manganese binding site 1 out of 2 in 1xnz
Go back to
Manganese Binding Sites List in 1xnz
Manganese binding site 1 out
of 2 in the Crystal Structure of Mn(II) Form of E. Coli. Methionine Aminopeptidase in Complex with 5-(2-Chlorophenyl)Furan-2- Carboxylic Acid
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 1 of Crystal Structure of Mn(II) Form of E. Coli. Methionine Aminopeptidase in Complex with 5-(2-Chlorophenyl)Furan-2- Carboxylic Acid within 5.0Å range:
|
Manganese binding site 2 out of 2 in 1xnz
Go back to
Manganese Binding Sites List in 1xnz
Manganese binding site 2 out
of 2 in the Crystal Structure of Mn(II) Form of E. Coli. Methionine Aminopeptidase in Complex with 5-(2-Chlorophenyl)Furan-2- Carboxylic Acid
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 2 of Crystal Structure of Mn(II) Form of E. Coli. Methionine Aminopeptidase in Complex with 5-(2-Chlorophenyl)Furan-2- Carboxylic Acid within 5.0Å range:
|
Reference:
Q.-Z.Ye,
S.-X.Xie,
M.Huang,
W.-J.Huang,
J.-P.Lu,
Z.-Q.Ma.
Metalloform-Selective Inhibitors of Escherichia Coli Methionine Aminopeptidase and X-Ray Structure of A Mn(II)-Form Enzyme Complexed with An Inhibitor. J.Am.Chem.Soc. V. 126 13940 2004.
ISSN: ISSN 0002-7863
PubMed: 15506752
DOI: 10.1021/JA045864P
Page generated: Sat Oct 5 13:08:10 2024
ISSN: ISSN 0002-7863
PubMed: 15506752
DOI: 10.1021/JA045864P
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