Manganese in PDB 1q0p: A Domain of Factor B

All present enzymatic activity of A Domain of Factor B:
3.4.21.47;

The structure of A Domain of Factor B, PDB code: 1q0p was solved by A.A.Bhattacharya, R.C.Liddington, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.00 / 1.80
Space group	P 63
Cell size a, b, c (Å), α, β, γ (°)	72.560, 72.560, 76.060, 90.00, 90.00, 120.00
R / Rfree (%)	21 / 25.9

The binding sites of Manganese atom in the A Domain of Factor B (pdb code 1q0p). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the A Domain of Factor B, PDB code: 1q0p:

Manganese binding site 1 out of 1 in the A Domain of Factor B


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of A Domain of Factor B within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn500 b:22.7 occ:1.00 OG A:SER255 2.1 25.4 1.0 OG A:SER253 2.1 23.0 1.0 O A:HOH71 2.1 20.4 1.0 OG1 A:THR328 2.2 23.5 1.0 O A:HOH5 2.2 21.8 1.0 CB A:SER253 3.1 22.7 1.0 CB A:SER255 3.2 26.4 1.0 CB A:THR328 3.4 20.1 1.0 CG2 A:THR328 3.7 16.3 1.0 N A:SER255 4.0 21.0 1.0 CA A:SER255 4.2 23.9 1.0 OD1 A:ASP364 4.2 21.8 1.0 OD1 A:ASP251 4.2 23.5 1.0 O A:LEU366 4.2 19.9 1.0 OD2 A:ASP251 4.2 19.3 1.0 OD2 A:ASP364 4.3 24.3 1.0 CA A:SER253 4.4 24.9 1.0 C A:SER253 4.5 25.5 1.0 CA A:THR328 4.6 21.3 1.0 CG A:ASP251 4.7 21.1 1.0 CG A:ASP364 4.7 24.8 1.0 N A:ASP254 4.8 29.0 1.0 N A:ILE256 4.8 24.4 1.0 CB A:LEU366 4.8 19.0 1.0 O A:SER253 4.9 26.7 1.0 ND2 A:ASN368 4.9 27.8 1.0 C A:SER255 4.9 22.2 1.0 C A:LEU366 5.0 17.8 1.0 N A:THR328 5.0 21.2 1.0

A.A.Bhattacharya, M.L.Lupher Jr., D.E.Staunton, R.C.Liddington. Crystal Structure of the A Domain From Complement Factor B Reveals An Integrin-Like Open Conformation. Structure V. 12 371 2004.
ISSN: ISSN 0969-2126
PubMed: 15016353
DOI: 10.1016/J.STR.2004.02.012