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Manganese in PDB 1pzy: W314A-BETA1,4-Galactosyltransferase-I Complexed with Alpha-Lactalbumin in the Presence of N-Acetylglucosamine, Udp and Manganese
Enzymatic activity of W314A-BETA1,4-Galactosyltransferase-I Complexed with Alpha-Lactalbumin in the Presence of N-Acetylglucosamine, Udp and Manganese
All present enzymatic activity of W314A-BETA1,4-Galactosyltransferase-I Complexed with Alpha-Lactalbumin in the Presence of N-Acetylglucosamine, Udp and Manganese:
2.4.1.22; 2.4.1.38; 2.4.1.90;
2.4.1.22; 2.4.1.38; 2.4.1.90;
Protein crystallography data
The structure of W314A-BETA1,4-Galactosyltransferase-I Complexed with Alpha-Lactalbumin in the Presence of N-Acetylglucosamine, Udp and Manganese, PDB code: 1pzy
was solved by
V.Ramasamy,
B.Ramakrishnan,
E.Boeggeman,
P.K.Qasba,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 19.95 / 2.30 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 55.292, 98.747, 102.788, 90.00, 103.92, 90.00 |
| R / Rfree (%) | 20.7 / 25.3 |
Other elements in 1pzy:
The structure of W314A-BETA1,4-Galactosyltransferase-I Complexed with Alpha-Lactalbumin in the Presence of N-Acetylglucosamine, Udp and Manganese also contains other interesting chemical elements:
| Calcium | (Ca) | 2 atoms |
Manganese Binding Sites:
The binding sites of Manganese atom in the W314A-BETA1,4-Galactosyltransferase-I Complexed with Alpha-Lactalbumin in the Presence of N-Acetylglucosamine, Udp and Manganese
(pdb code 1pzy). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the W314A-BETA1,4-Galactosyltransferase-I Complexed with Alpha-Lactalbumin in the Presence of N-Acetylglucosamine, Udp and Manganese, PDB code: 1pzy:
Jump to Manganese binding site number: 1; 2;
In total 2 binding sites of Manganese where determined in the W314A-BETA1,4-Galactosyltransferase-I Complexed with Alpha-Lactalbumin in the Presence of N-Acetylglucosamine, Udp and Manganese, PDB code: 1pzy:
Jump to Manganese binding site number: 1; 2;
Manganese binding site 1 out of 2 in 1pzy
Go back to
Manganese Binding Sites List in 1pzy
Manganese binding site 1 out
of 2 in the W314A-BETA1,4-Galactosyltransferase-I Complexed with Alpha-Lactalbumin in the Presence of N-Acetylglucosamine, Udp and Manganese
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 1 of W314A-BETA1,4-Galactosyltransferase-I Complexed with Alpha-Lactalbumin in the Presence of N-Acetylglucosamine, Udp and Manganese within 5.0Å range:
|
Manganese binding site 2 out of 2 in 1pzy
Go back to
Manganese Binding Sites List in 1pzy
Manganese binding site 2 out
of 2 in the W314A-BETA1,4-Galactosyltransferase-I Complexed with Alpha-Lactalbumin in the Presence of N-Acetylglucosamine, Udp and Manganese
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 2 of W314A-BETA1,4-Galactosyltransferase-I Complexed with Alpha-Lactalbumin in the Presence of N-Acetylglucosamine, Udp and Manganese within 5.0Å range:
|
Reference:
V.Ramasamy,
B.Ramakrishnan,
E.Boeggeman,
P.K.Qasba.
The Role of Tryptophan 314 in the Conformational Changes of Beta 1,4-Galactosyltransferase-I J.Mol.Biol. V. 331 1065 2003.
ISSN: ISSN 0022-2836
PubMed: 12927542
DOI: 10.1016/S0022-2836(03)00790-3
Page generated: Sat Oct 5 12:08:49 2024
ISSN: ISSN 0022-2836
PubMed: 12927542
DOI: 10.1016/S0022-2836(03)00790-3
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