Manganese in PDB 1on6: Crystal Structure of Mouse Alpha-1,4-N-Acetylhexosaminotransferase (EXTL2) in Complex with Udpglcnac

The structure of Crystal Structure of Mouse Alpha-1,4-N-Acetylhexosaminotransferase (EXTL2) in Complex with Udpglcnac, PDB code: 1on6 was solved by L.C.Pedersen, J.Dong, F.Taniguchi, H.Kitagawa, J.M.Krahn, L.G.Pedersen, K.Sugahara, M.Negishi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.93 / 2.30
Space group	P 4 21 2
Cell size a, b, c (Å), α, β, γ (°)	126.064, 126.064, 83.936, 90.00, 90.00, 90.00
R / Rfree (%)	19.6 / 23.4

The binding sites of Manganese atom in the Crystal Structure of Mouse Alpha-1,4-N-Acetylhexosaminotransferase (EXTL2) in Complex with Udpglcnac (pdb code 1on6). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Crystal Structure of Mouse Alpha-1,4-N-Acetylhexosaminotransferase (EXTL2) in Complex with Udpglcnac, PDB code: 1on6:
Jump to Manganese binding site number: 1; 2;

Manganese binding site 1 out of 2 in the Crystal Structure of Mouse Alpha-1,4-N-Acetylhexosaminotransferase (EXTL2) in Complex with Udpglcnac


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Crystal Structure of Mouse Alpha-1,4-N-Acetylhexosaminotransferase (EXTL2) in Complex with Udpglcnac within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn600 b:65.1 occ:1.00 O2A A:UD1401 2.1 44.9 1.0 O2B A:UD1401 2.1 46.0 1.0 O A:HOH690 2.1 40.2 1.0 O A:HOH691 2.3 44.5 1.0 OD2 A:ASP153 2.3 33.0 1.0 O A:HOH656 2.4 48.0 1.0 PA A:UD1401 3.3 43.0 1.0 CG A:ASP153 3.3 33.9 1.0 PB A:UD1401 3.3 46.0 1.0 O3A A:UD1401 3.5 45.5 1.0 OD1 A:ASP153 3.6 31.9 1.0 NH2 A:ARG76 3.9 35.8 1.0 O1' A:UD1401 3.9 51.3 1.0 NH1 A:ARG76 4.1 36.2 1.0 O1A A:UD1401 4.1 46.7 1.0 ND2 A:ASN272 4.2 39.0 1.0 OE2 A:GLU274 4.3 65.6 1.0 OD2 A:ASP151 4.4 32.7 1.0 CZ A:ARG76 4.4 38.1 1.0 O1B A:UD1401 4.5 45.9 1.0 O5B A:UD1401 4.5 44.2 1.0 CB A:ASP153 4.6 33.0 1.0 C5B A:UD1401 4.8 43.3 1.0 O A:HOH625 4.9 39.2 1.0 CB A:ASP151 4.9 26.8 1.0

Manganese binding site 2 out of 2 in the Crystal Structure of Mouse Alpha-1,4-N-Acetylhexosaminotransferase (EXTL2) in Complex with Udpglcnac


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Crystal Structure of Mouse Alpha-1,4-N-Acetylhexosaminotransferase (EXTL2) in Complex with Udpglcnac within 5.0Å range: probe atom residue distance (Å) B Occ B:Mn601 b:53.2 occ:1.00 O2B B:UD1400 2.0 45.9 1.0 OD2 B:ASP153 2.0 33.2 1.0 O B:HOH654 2.3 29.1 1.0 O2A B:UD1400 2.3 42.0 1.0 O B:HOH684 2.3 38.2 1.0 O B:HOH683 2.4 24.1 1.0 CG B:ASP153 3.1 33.5 1.0 PB B:UD1400 3.3 45.9 1.0 PA B:UD1400 3.4 41.6 1.0 OD1 B:ASP153 3.6 32.4 1.0 O3A B:UD1400 3.6 43.7 1.0 ND2 B:ASN272 3.9 41.6 1.0 NH2 B:ARG76 4.0 34.7 1.0 O1' B:UD1400 4.0 50.5 1.0 O1A B:UD1400 4.0 40.8 1.0 NH1 B:ARG76 4.3 36.7 1.0 CB B:ASP153 4.3 32.3 1.0 O1B B:UD1400 4.4 46.3 1.0 CZ B:ARG76 4.6 36.6 1.0 O5B B:UD1400 4.7 38.3 1.0 OD2 B:ASP151 4.7 33.9 1.0 CG B:ASN272 5.0 43.8 1.0

L.C.Pedersen, J.Dong, F.Taniguchi, H.Kitagawa, J.M.Krahn, L.G.Pedersen, K.Sugahara, M.Negishi. Crystal Structure of An Alpha-1,4-N-Acetylhexosaminyltransferase (EXTL2), A Member of the Exostosin Gene Family Involved in Heparan Sulfate Biosynthesis J.Biol.Chem. V. 278 14420 2003.
ISSN: ISSN 0021-9258
PubMed: 12562774
DOI: 10.1074/JBC.M210532200