Manganese in PDB 1mwh: Reovirus Polymerase LAMBDA3 Bound to Mrna Cap Analog

The structure of Reovirus Polymerase LAMBDA3 Bound to Mrna Cap Analog, PDB code: 1mwh was solved by Y.Tao, D.L.Farsetta, M.L.Nibert, S.C.Harrison, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.88 / 2.50
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	70.891, 84.944, 249.246, 90.00, 90.00, 90.00
R / Rfree (%)	20.9 / 24.5

The binding sites of Manganese atom in the Reovirus Polymerase LAMBDA3 Bound to Mrna Cap Analog (pdb code 1mwh). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Reovirus Polymerase LAMBDA3 Bound to Mrna Cap Analog, PDB code: 1mwh:

Manganese binding site 1 out of 1 in the Reovirus Polymerase LAMBDA3 Bound to Mrna Cap Analog


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Reovirus Polymerase LAMBDA3 Bound to Mrna Cap Analog within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn1500 b:54.3 occ:1.00 OD1 A:ASP735 1.5 40.6 1.0 OE1 A:GLU780 1.9 44.8 1.0 OD1 A:ASP585 2.2 38.5 1.0 O A:HOH2382 2.3 37.5 1.0 O A:HOH2433 2.3 58.3 1.0 CG A:ASP735 2.5 39.1 1.0 OD2 A:ASP585 2.7 38.6 1.0 CG A:ASP585 2.8 38.5 1.0 OD2 A:ASP735 2.8 40.3 1.0 CD A:GLU780 2.9 43.2 1.0 OE2 A:GLU780 3.3 45.9 1.0 O A:GLU780 3.7 34.3 1.0 CB A:ASP735 3.8 35.8 1.0 O A:HOH2349 4.0 45.9 1.0 O A:HOH2423 4.1 50.1 1.0 CG A:GLU780 4.3 39.6 1.0 CA A:ASP735 4.3 36.0 1.0 CB A:ASP585 4.3 36.5 1.0 O A:ILE584 4.3 37.5 1.0 C A:GLU780 4.3 32.2 1.0 O A:GLY736 4.3 35.2 1.0 N A:GLY736 4.4 36.2 1.0 CB A:ASN583 4.6 31.7 1.0 CB A:GLU780 4.7 35.0 1.0 CA A:TYR781 4.7 30.9 1.0 C A:ILE584 4.8 36.1 1.0 C A:ASP735 4.8 35.9 1.0 N A:TYR781 4.8 31.6 1.0

Y.Tao, D.L.Farsetta, M.L.Nibert, S.C.Harrison. Rna Synthesis in A Cage-Structural Studies of Reovirus Polymerase LAMBDA3 Cell(Cambridge,Mass.) V. 111 733 2002.
ISSN: ISSN 0092-8674
PubMed: 12464184
DOI: 10.1016/S0092-8674(02)01110-8