Manganese in PDB 1m51: Pepck Complex with A Gtp-Competitive Inhibitor

All present enzymatic activity of Pepck Complex with A Gtp-Competitive Inhibitor:
4.1.1.32;

The structure of Pepck Complex with A Gtp-Competitive Inhibitor, PDB code: 1m51 was solved by L.H.Foley, P.Wang, P.Dunten, S.J.Wertheimer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.25
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	45.407, 61.067, 62.007, 88.91, 70.21, 72.62
R / Rfree (%)	17.8 / 23.7

The binding sites of Manganese atom in the Pepck Complex with A Gtp-Competitive Inhibitor (pdb code 1m51). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Pepck Complex with A Gtp-Competitive Inhibitor, PDB code: 1m51:

Manganese binding site 1 out of 1 in the Pepck Complex with A Gtp-Competitive Inhibitor


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Pepck Complex with A Gtp-Competitive Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn701 b:8.7 occ:0.25 NZ A:LYS244 1.9 12.8 1.0 NE2 A:HIS264 2.2 13.9 1.0 O A:HOH1068 2.2 16.1 1.0 OD1 A:ASP311 2.3 9.0 1.0 CE1 A:HIS264 3.0 13.6 1.0 CE A:LYS244 3.2 10.5 1.0 CG A:ASP311 3.2 9.6 1.0 OD2 A:ASP311 3.3 8.4 1.0 CD2 A:HIS264 3.3 12.3 1.0 NZ A:LYS290 3.8 21.7 1.0 ND1 A:HIS264 4.2 12.7 1.0 O A:ACT1004 4.3 32.2 1.0 O A:HOH1075 4.4 16.5 1.0 CD A:LYS244 4.4 9.8 1.0 CG A:HIS264 4.4 10.5 1.0 CB A:ASP311 4.6 7.0 1.0 O A:HOH1185 4.7 18.9 1.0 CH3 A:ACT1004 4.8 31.9 1.0 CE1 A:PHE485 4.9 9.9 1.0 CZ A:PHE485 5.0 7.2 1.0 C A:ACT1004 5.0 32.5 1.0

L.H.Foley, P.Wang, P.Dunten, G.Ramsey, M.-L.Gubler, S.J.Wertheimer. X-Ray Structures of Two Xanthine Inhibitors Bound to Pepck and N-3 Modifications of Substituted 1,8-Dibenzylxanthines Bioorg.Med.Chem.Lett. V. 13 3871 2003.
ISSN: ISSN 0960-894X
PubMed: 14552798
DOI: 10.1016/S0960-894X(03)00723-6