Manganese in PDB 1loa: Three-Dimensional Structures of Complexes of Lathyrus Ochrus Isolectin I with Glucose and Mannose: Fine Specificity of the Monosaccharide-Binding Site

The structure of Three-Dimensional Structures of Complexes of Lathyrus Ochrus Isolectin I with Glucose and Mannose: Fine Specificity of the Monosaccharide-Binding Site, PDB code: 1loa was solved by Y.Bourne, C.Cambillau, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	8.00 / 2.20
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	56.300, 139.800, 62.700, 90.00, 91.00, 90.00
R / Rfree (%)	17.9 / n/a

The structure of Three-Dimensional Structures of Complexes of Lathyrus Ochrus Isolectin I with Glucose and Mannose: Fine Specificity of the Monosaccharide-Binding Site also contains other interesting chemical elements:

Calcium

(Ca)

4 atoms

The binding sites of Manganese atom in the Three-Dimensional Structures of Complexes of Lathyrus Ochrus Isolectin I with Glucose and Mannose: Fine Specificity of the Monosaccharide-Binding Site (pdb code 1loa). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 4 binding sites of Manganese where determined in the Three-Dimensional Structures of Complexes of Lathyrus Ochrus Isolectin I with Glucose and Mannose: Fine Specificity of the Monosaccharide-Binding Site, PDB code: 1loa:
Jump to Manganese binding site number: 1; 2; 3; 4;

Manganese binding site 1 out of 4 in the Three-Dimensional Structures of Complexes of Lathyrus Ochrus Isolectin I with Glucose and Mannose: Fine Specificity of the Monosaccharide-Binding Site


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Three-Dimensional Structures of Complexes of Lathyrus Ochrus Isolectin I with Glucose and Mannose: Fine Specificity of the Monosaccharide-Binding Site within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn229 b:30.8 occ:1.00 O A:HOH270 1.5 39.8 1.0 O A:HOH276 1.5 22.0 1.0 NE2 A:HIS136 2.1 16.9 1.0 OE2 A:GLU119 2.1 10.6 1.0 OD1 A:ASP129 2.2 17.2 1.0 OD2 A:ASP121 2.3 23.5 1.0 CD2 A:HIS136 2.8 17.0 1.0 CD A:GLU119 3.2 14.2 1.0 CE1 A:HIS136 3.2 15.5 1.0 CG A:ASP121 3.3 20.9 1.0 CG A:ASP129 3.4 21.0 1.0 OE1 A:GLU119 3.5 14.8 1.0 CB A:ASP121 3.7 19.7 1.0 OD2 A:ASP129 4.0 19.9 1.0 O A:HOH269 4.0 11.7 1.0 CG A:HIS136 4.1 18.1 1.0 OG A:SER146 4.1 21.6 1.0 ND1 A:HIS136 4.2 16.8 1.0 OD1 A:ASP121 4.4 21.4 1.0 CB A:ASP129 4.5 21.1 1.0 CG A:GLU119 4.5 13.2 1.0 O A:ILE144 4.6 19.2 1.0 CA A:CA228 4.7 27.2 1.0 CA A:ASP129 4.8 24.8 1.0 CD A:PRO130 4.8 30.1 1.0 CD1 A:TRP128 4.9 29.7 1.0 NE1 A:TRP128 4.9 30.6 1.0

Manganese binding site 2 out of 4 in the Three-Dimensional Structures of Complexes of Lathyrus Ochrus Isolectin I with Glucose and Mannose: Fine Specificity of the Monosaccharide-Binding Site


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Three-Dimensional Structures of Complexes of Lathyrus Ochrus Isolectin I with Glucose and Mannose: Fine Specificity of the Monosaccharide-Binding Site within 5.0Å range: probe atom residue distance (Å) B Occ C:Mn459 b:41.9 occ:1.00 O C:HOH493 1.5 47.9 1.0 O C:HOH492 1.5 31.2 1.0 OD2 C:ASP121 2.0 35.6 1.0 OD1 C:ASP129 2.4 31.6 1.0 OE2 C:GLU119 2.4 23.3 1.0 O C:HOH471 2.9 62.0 1.0 OD2 C:ASP129 3.1 35.8 1.0 CG C:ASP129 3.1 33.4 1.0 CG C:ASP121 3.2 35.0 1.0 NE2 C:HIS136 3.2 36.4 1.0 CD C:GLU119 3.2 25.1 1.0 OE1 C:GLU119 3.4 22.4 1.0 O C:HOH491 3.6 30.9 1.0 OG C:SER146 3.8 26.6 1.0 CB C:ASP121 4.0 32.2 1.0 CD2 C:HIS136 4.0 36.1 1.0 OD1 C:ASP121 4.1 34.1 1.0 O C:ILE144 4.2 32.1 1.0 CE1 C:HIS136 4.2 38.4 1.0 CD1 C:TRP128 4.5 42.3 1.0 CB C:ASP129 4.5 34.9 1.0 CG C:GLU119 4.6 24.3 1.0 CA C:CA458 4.7 36.8 1.0 NE1 C:TRP128 4.7 42.6 1.0 CA C:ASP129 5.0 36.9 1.0

Manganese binding site 3 out of 4 in the Three-Dimensional Structures of Complexes of Lathyrus Ochrus Isolectin I with Glucose and Mannose: Fine Specificity of the Monosaccharide-Binding Site


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 3 of Three-Dimensional Structures of Complexes of Lathyrus Ochrus Isolectin I with Glucose and Mannose: Fine Specificity of the Monosaccharide-Binding Site within 5.0Å range: probe atom residue distance (Å) B Occ F:Mn689 b:29.6 occ:1.00 OH F:TYR4 1.5 29.8 1.0 O E:HOH739 1.6 24.8 1.0 CZ F:TYR4 2.7 28.6 1.0 O E:ALA153 3.2 33.1 1.0 CB E:ALA153 3.3 28.4 1.0 CE2 F:TYR4 3.3 27.5 1.0 CG2 F:THR2 3.4 34.3 1.0 N E:ALA153 3.5 27.5 1.0 CE1 F:TYR4 3.7 25.0 1.0 CA E:ALA153 3.8 28.9 1.0 C E:ALA153 4.0 30.4 1.0 OE1 E:GLN155 4.0 44.0 1.0 C E:TRP152 4.6 25.4 1.0 CD1 E:TRP152 4.7 30.7 1.0 CB F:THR2 4.7 31.9 1.0 CD2 F:TYR4 4.7 28.1 1.0 CE2 E:TYR179 4.8 25.1 1.0 CD2 E:TYR179 4.8 25.3 1.0 CD1 F:TYR4 4.9 26.5 1.0 CA E:TRP152 4.9 25.7 1.0

Manganese binding site 4 out of 4 in the Three-Dimensional Structures of Complexes of Lathyrus Ochrus Isolectin I with Glucose and Mannose: Fine Specificity of the Monosaccharide-Binding Site


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 4 of Three-Dimensional Structures of Complexes of Lathyrus Ochrus Isolectin I with Glucose and Mannose: Fine Specificity of the Monosaccharide-Binding Site within 5.0Å range: probe atom residue distance (Å) B Occ G:Mn919 b:28.9 occ:1.00 O G:HOH949 1.5 35.3 1.0 O G:HOH948 1.6 17.5 1.0 OD2 G:ASP121 2.1 25.0 1.0 OE2 G:GLU119 2.3 26.6 1.0 NE2 G:HIS136 2.4 18.0 1.0 OD1 G:ASP129 2.6 32.5 1.0 CD G:GLU119 3.2 26.7 1.0 CD2 G:HIS136 3.2 17.6 1.0 CG G:ASP121 3.2 21.4 1.0 CE1 G:HIS136 3.4 19.4 1.0 CG G:ASP129 3.4 32.4 1.0 OE1 G:GLU119 3.6 22.2 1.0 CB G:ASP121 3.8 20.7 1.0 OD2 G:ASP129 3.8 32.8 1.0 OG G:SER146 3.9 24.2 1.0 O G:HOH947 3.9 14.8 1.0 O G:HOH928 4.2 29.2 1.0 OD1 G:ASP121 4.2 24.8 1.0 CG G:GLU119 4.3 26.9 1.0 CG G:HIS136 4.4 19.2 1.0 ND1 G:HIS136 4.5 19.5 1.0 NE1 G:TRP128 4.5 35.9 1.0 O G:ILE144 4.5 22.6 1.0 CD1 G:TRP128 4.5 35.4 1.0 CA G:CA918 4.5 33.7 1.0 CB G:ASP129 4.6 34.5 1.0 CD G:PRO130 4.7 37.8 1.0 CA G:ASP129 4.8 36.5 1.0

Y.Bourne, A.Roussel, M.Frey, P.Rouge, J.C.Fontecilla-Camps, C.Cambillau. Three-Dimensional Structures of Complexes of Lathyrus Ochrus Isolectin I with Glucose and Mannose: Fine Specificity of the Monosaccharide-Binding Site. Proteins V. 8 365 1990.
ISSN: ISSN 0887-3585
PubMed: 2091026
DOI: 10.1002/PROT.340080410