Manganese in PDB 1lgc: Interaction of A Legume Lectin with the N2 Fragment of Human Lactotransferrin or with the Isolated Biantennary Glycopeptide: Role of the Fucose Moiety

The structure of Interaction of A Legume Lectin with the N2 Fragment of Human Lactotransferrin or with the Isolated Biantennary Glycopeptide: Role of the Fucose Moiety, PDB code: 1lgc was solved by Y.Bourne, C.Cambillau, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	6.00 / 2.80
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	117.000, 117.000, 120.100, 90.00, 90.00, 90.00
R / Rfree (%)	18.5 / n/a

The structure of Interaction of A Legume Lectin with the N2 Fragment of Human Lactotransferrin or with the Isolated Biantennary Glycopeptide: Role of the Fucose Moiety also contains other interesting chemical elements:

Calcium

(Ca)

3 atoms

The binding sites of Manganese atom in the Interaction of A Legume Lectin with the N2 Fragment of Human Lactotransferrin or with the Isolated Biantennary Glycopeptide: Role of the Fucose Moiety (pdb code 1lgc). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 3 binding sites of Manganese where determined in the Interaction of A Legume Lectin with the N2 Fragment of Human Lactotransferrin or with the Isolated Biantennary Glycopeptide: Role of the Fucose Moiety, PDB code: 1lgc:
Jump to Manganese binding site number: 1; 2; 3;

Manganese binding site 1 out of 3 in the Interaction of A Legume Lectin with the N2 Fragment of Human Lactotransferrin or with the Isolated Biantennary Glycopeptide: Role of the Fucose Moiety


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Interaction of A Legume Lectin with the N2 Fragment of Human Lactotransferrin or with the Isolated Biantennary Glycopeptide: Role of the Fucose Moiety within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn302 b:40.9 occ:1.00 OE2 A:GLU119 2.2 29.1 1.0 OD1 A:ASP129 2.5 35.2 1.0 OD2 A:ASP121 2.8 33.6 1.0 CD A:GLU119 2.9 21.9 1.0 OE1 A:GLU119 2.9 18.3 1.0 NE2 A:HIS136 3.1 18.7 1.0 CG A:ASP129 3.6 38.8 1.0 CG A:ASP121 3.7 27.9 1.0 OG A:SER146 3.7 33.3 1.0 CB A:ASP121 3.7 21.1 1.0 O A:ILE144 4.0 22.0 1.0 CD2 A:HIS136 4.0 21.2 1.0 CE1 A:HIS136 4.0 17.3 1.0 OD2 A:ASP129 4.1 38.2 1.0 O A:HOH329 4.2 15.7 1.0 CD1 A:ILE144 4.2 34.7 1.0 O A:HOH374 4.3 12.9 1.0 CG A:GLU119 4.4 24.0 1.0 NE1 A:TRP128 4.6 27.1 1.0 CD1 A:TRP128 4.7 24.3 1.0 CB A:ASP129 4.9 35.2 1.0 OD1 A:ASP121 4.9 25.0 1.0 OD1 A:ASP140 4.9 19.4 1.0 CB A:SER146 5.0 22.9 1.0

Manganese binding site 2 out of 3 in the Interaction of A Legume Lectin with the N2 Fragment of Human Lactotransferrin or with the Isolated Biantennary Glycopeptide: Role of the Fucose Moiety


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Interaction of A Legume Lectin with the N2 Fragment of Human Lactotransferrin or with the Isolated Biantennary Glycopeptide: Role of the Fucose Moiety within 5.0Å range: probe atom residue distance (Å) B Occ C:Mn302 b:38.5 occ:1.00 OD1 C:ASP129 2.4 48.2 1.0 OG C:SER146 2.9 39.9 1.0 OE2 C:GLU119 3.0 36.8 1.0 NE2 C:HIS136 3.1 52.3 1.0 OD2 C:ASP121 3.4 38.2 1.0 CG C:ASP129 3.6 51.8 1.0 CD C:GLU119 3.7 34.1 1.0 O C:ILE144 3.9 44.5 1.0 CD2 C:HIS136 4.0 47.2 1.0 OE1 C:GLU119 4.0 29.1 1.0 CE1 C:HIS136 4.0 50.0 1.0 CB C:ASP121 4.0 31.5 1.0 CG C:ASP121 4.2 40.6 1.0 CB C:SER146 4.2 34.6 1.0 OD2 C:ASP129 4.2 59.0 1.0 O C:TRP128 4.6 43.0 1.0 N C:SER146 4.6 33.8 1.0 CB C:ASP129 4.7 48.7 1.0 CD1 C:TRP128 4.7 39.0 1.0 CG C:GLU119 4.8 28.1 1.0 CA C:ASP129 4.8 44.0 1.0

Manganese binding site 3 out of 3 in the Interaction of A Legume Lectin with the N2 Fragment of Human Lactotransferrin or with the Isolated Biantennary Glycopeptide: Role of the Fucose Moiety


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 3 of Interaction of A Legume Lectin with the N2 Fragment of Human Lactotransferrin or with the Isolated Biantennary Glycopeptide: Role of the Fucose Moiety within 5.0Å range: probe atom residue distance (Å) B Occ E:Mn302 b:40.0 occ:1.00 O E:HOH324 2.0 47.5 1.0 OE2 E:GLU119 2.3 45.6 1.0 OD1 E:ASP129 2.5 38.7 1.0 OD2 E:ASP121 2.8 29.2 1.0 NE2 E:HIS136 2.8 26.6 1.0 CD E:GLU119 3.1 43.5 1.0 OE1 E:GLU119 3.2 41.3 1.0 CB E:ASP121 3.4 31.7 1.0 CE1 E:HIS136 3.4 26.1 1.0 CG E:ASP121 3.5 35.5 1.0 CG E:ASP129 3.6 42.5 1.0 CD2 E:HIS136 3.9 31.2 1.0 OD2 E:ASP129 3.9 45.7 1.0 O E:ILE144 4.2 45.9 1.0 OG E:SER146 4.5 30.2 1.0 CG E:GLU119 4.5 40.3 1.0 ND1 E:HIS136 4.6 30.6 1.0 OD1 E:ASP121 4.7 38.4 1.0 CD1 E:TRP128 4.8 35.1 1.0 CB E:ASP129 4.9 35.8 1.0 CA E:ASP121 4.9 30.5 1.0 NE1 E:TRP128 4.9 42.6 1.0 CG E:HIS136 4.9 34.3 1.0 CD E:PRO130 4.9 38.5 1.0

Y.Bourne, J.Mazurier, D.Legrand, P.Rouge, J.Montreuil, G.Spik, C.Cambillau. Structures of A Legume Lectin Complexed with the Human Lactotransferrin N2 Fragment, and with An Isolated Biantennary Glycopeptide: Role of the Fucose Moiety. Structure V. 2 209 1994.
ISSN: ISSN 0969-2126
PubMed: 8069634
DOI: 10.1016/S0969-2126(00)00022-8