Manganese in PDB 1hpu: 5'-Nucleotidase (Closed Form), Complex with Ampcp
Enzymatic activity of 5'-Nucleotidase (Closed Form), Complex with Ampcp
All present enzymatic activity of 5'-Nucleotidase (Closed Form), Complex with Ampcp:
3.1.3.5;
3.6.1.45;
Protein crystallography data
The structure of 5'-Nucleotidase (Closed Form), Complex with Ampcp, PDB code: 1hpu
was solved by
T.Knoefel,
N.Straeter,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
28.59 /
1.85
|
|
Space group
|
P 1
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
89.400,
89.960,
96.260,
110.79,
106.43,
107.76
|
|
R / Rfree (%)
|
20.7 /
23.4
|
Manganese Binding Sites:
The binding sites of Manganese atom in the 5'-Nucleotidase (Closed Form), Complex with Ampcp
(pdb code 1hpu). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total 8 binding sites of Manganese where determined in the
5'-Nucleotidase (Closed Form), Complex with Ampcp, PDB code: 1hpu:
Jump to Manganese binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Manganese binding site 1 out
of 8 in 1hpu
Go back to
Manganese Binding Sites List in 1hpu
Manganese binding site 1 out
of 8 in the 5'-Nucleotidase (Closed Form), Complex with Ampcp
 Mono view
 Stereo pair view
|
|
A full contact list of Manganese with other atoms in the Mn binding
site number 1 of 5'-Nucleotidase (Closed Form), Complex with Ampcp within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mn600
b:26.1
occ:1.00
|
O1B
|
A:A121602
|
2.2
|
28.5
|
1.0
|
|
OD1
|
A:ASN116
|
2.2
|
26.9
|
1.0
|
|
NE2
|
A:HIS217
|
2.2
|
25.3
|
1.0
|
|
O
|
A:HOH1669
|
2.3
|
25.6
|
1.0
|
|
ND1
|
A:HIS252
|
2.3
|
24.9
|
1.0
|
|
OD2
|
A:ASP84
|
2.4
|
22.4
|
1.0
|
|
CE1
|
A:HIS252
|
3.1
|
25.5
|
1.0
|
|
CG
|
A:ASN116
|
3.2
|
27.9
|
1.0
|
|
CE1
|
A:HIS217
|
3.2
|
22.6
|
1.0
|
|
CG
|
A:ASP84
|
3.2
|
24.6
|
1.0
|
|
CD2
|
A:HIS217
|
3.2
|
24.0
|
1.0
|
|
OD1
|
A:ASP84
|
3.5
|
25.5
|
1.0
|
|
MN
|
A:MN601
|
3.5
|
47.0
|
1.0
|
|
CG
|
A:HIS252
|
3.5
|
23.1
|
1.0
|
|
ND2
|
A:ASN116
|
3.5
|
27.9
|
1.0
|
|
PB
|
A:A121602
|
3.5
|
34.1
|
1.0
|
|
O2B
|
A:A121602
|
3.8
|
35.5
|
1.0
|
|
CA
|
A:HIS252
|
3.8
|
21.3
|
1.0
|
|
CB
|
A:HIS252
|
4.0
|
22.2
|
1.0
|
|
CD2
|
A:HIS117
|
4.0
|
26.0
|
1.0
|
|
OD1
|
A:ASP41
|
4.2
|
21.5
|
1.0
|
|
NE2
|
A:HIS252
|
4.3
|
26.9
|
1.0
|
|
O
|
A:HIS252
|
4.3
|
25.8
|
1.0
|
|
ND1
|
A:HIS217
|
4.3
|
22.1
|
1.0
|
|
CG
|
A:HIS217
|
4.4
|
26.6
|
1.0
|
|
CB
|
A:ASP84
|
4.5
|
22.2
|
1.0
|
|
CD2
|
A:HIS252
|
4.5
|
28.2
|
1.0
|
|
C3A
|
A:A121602
|
4.5
|
35.5
|
1.0
|
|
N
|
A:ASN116
|
4.5
|
25.8
|
1.0
|
|
O3B
|
A:A121602
|
4.5
|
30.9
|
1.0
|
|
C
|
A:HIS252
|
4.6
|
21.5
|
1.0
|
|
CB
|
A:ASN116
|
4.6
|
28.4
|
1.0
|
|
NE2
|
A:HIS117
|
4.7
|
27.3
|
1.0
|
|
N
|
A:HIS252
|
4.8
|
20.3
|
1.0
|
|
Manganese binding site 2 out
of 8 in 1hpu
Go back to
Manganese Binding Sites List in 1hpu
Manganese binding site 2 out
of 8 in the 5'-Nucleotidase (Closed Form), Complex with Ampcp
 Mono view
 Stereo pair view
|
|
A full contact list of Manganese with other atoms in the Mn binding
site number 2 of 5'-Nucleotidase (Closed Form), Complex with Ampcp within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mn601
b:47.0
occ:1.00
|
OD1
|
A:ASP41
|
2.1
|
21.5
|
1.0
|
|
O
|
A:HOH1669
|
2.2
|
25.6
|
1.0
|
|
NE2
|
A:HIS43
|
2.3
|
27.2
|
1.0
|
|
OE1
|
A:GLN254
|
2.3
|
28.9
|
1.0
|
|
OD2
|
A:ASP84
|
2.4
|
22.4
|
1.0
|
|
CE1
|
A:HIS43
|
3.2
|
25.4
|
1.0
|
|
CG
|
A:ASP41
|
3.2
|
25.1
|
1.0
|
|
CD2
|
A:HIS43
|
3.3
|
25.2
|
1.0
|
|
CD
|
A:GLN254
|
3.3
|
27.0
|
1.0
|
|
CG
|
A:ASP84
|
3.4
|
24.6
|
1.0
|
|
MN
|
A:MN600
|
3.5
|
26.1
|
1.0
|
|
CB
|
A:ASP84
|
3.6
|
22.2
|
1.0
|
|
O2B
|
A:A121602
|
3.7
|
35.5
|
1.0
|
|
CB
|
A:ASP41
|
3.8
|
21.9
|
1.0
|
|
CG
|
A:GLN254
|
3.9
|
24.8
|
1.0
|
|
CE1
|
A:HIS217
|
4.2
|
22.6
|
1.0
|
|
O1B
|
A:A121602
|
4.2
|
28.5
|
1.0
|
|
OD2
|
A:ASP41
|
4.2
|
22.4
|
1.0
|
|
O
|
A:HIS252
|
4.2
|
25.8
|
1.0
|
|
ND1
|
A:HIS43
|
4.3
|
23.8
|
1.0
|
|
NE2
|
A:HIS217
|
4.4
|
25.3
|
1.0
|
|
NE2
|
A:GLN254
|
4.4
|
25.3
|
1.0
|
|
CG
|
A:HIS43
|
4.4
|
26.3
|
1.0
|
|
CA
|
A:ASP41
|
4.4
|
19.0
|
1.0
|
|
CA
|
A:HIS252
|
4.5
|
21.3
|
1.0
|
|
OD1
|
A:ASP84
|
4.5
|
25.5
|
1.0
|
|
PB
|
A:A121602
|
4.5
|
34.1
|
1.0
|
|
CD2
|
A:HIS117
|
4.6
|
26.0
|
1.0
|
|
C
|
A:HIS252
|
4.8
|
21.5
|
1.0
|
|
N
|
A:HIS252
|
4.9
|
20.3
|
1.0
|
|
Manganese binding site 3 out
of 8 in 1hpu
Go back to
Manganese Binding Sites List in 1hpu
Manganese binding site 3 out
of 8 in the 5'-Nucleotidase (Closed Form), Complex with Ampcp
 Mono view
 Stereo pair view
|
|
A full contact list of Manganese with other atoms in the Mn binding
site number 3 of 5'-Nucleotidase (Closed Form), Complex with Ampcp within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Mn600
b:24.0
occ:1.00
|
O1B
|
B:A121603
|
2.2
|
27.1
|
1.0
|
|
OD1
|
B:ASN116
|
2.2
|
25.0
|
1.0
|
|
ND1
|
B:HIS252
|
2.2
|
23.5
|
1.0
|
|
O
|
B:HOH1690
|
2.2
|
23.3
|
1.0
|
|
NE2
|
B:HIS217
|
2.3
|
23.6
|
1.0
|
|
OD2
|
B:ASP84
|
2.3
|
21.7
|
1.0
|
|
CE1
|
B:HIS252
|
3.0
|
26.9
|
1.0
|
|
CG
|
B:ASP84
|
3.2
|
23.5
|
1.0
|
|
CE1
|
B:HIS217
|
3.2
|
23.0
|
1.0
|
|
CG
|
B:ASN116
|
3.2
|
26.4
|
1.0
|
|
CD2
|
B:HIS217
|
3.2
|
22.7
|
1.0
|
|
CG
|
B:HIS252
|
3.4
|
25.3
|
1.0
|
|
MN
|
B:MN601
|
3.4
|
45.4
|
1.0
|
|
PB
|
B:A121603
|
3.5
|
27.9
|
1.0
|
|
OD1
|
B:ASP84
|
3.6
|
24.1
|
1.0
|
|
ND2
|
B:ASN116
|
3.6
|
22.5
|
1.0
|
|
CA
|
B:HIS252
|
3.8
|
22.9
|
1.0
|
|
CB
|
B:HIS252
|
3.9
|
22.0
|
1.0
|
|
O2B
|
B:A121603
|
3.9
|
29.6
|
1.0
|
|
CD2
|
B:HIS117
|
4.1
|
26.0
|
1.0
|
|
OD1
|
B:ASP41
|
4.2
|
19.1
|
1.0
|
|
NE2
|
B:HIS252
|
4.2
|
26.0
|
1.0
|
|
O
|
B:HIS252
|
4.2
|
21.9
|
1.0
|
|
ND1
|
B:HIS217
|
4.3
|
23.0
|
1.0
|
|
CG
|
B:HIS217
|
4.4
|
22.4
|
1.0
|
|
CD2
|
B:HIS252
|
4.4
|
27.7
|
1.0
|
|
CB
|
B:ASP84
|
4.4
|
19.9
|
1.0
|
|
C3A
|
B:A121603
|
4.5
|
31.4
|
1.0
|
|
O3B
|
B:A121603
|
4.5
|
28.6
|
1.0
|
|
C
|
B:HIS252
|
4.5
|
23.1
|
1.0
|
|
CB
|
B:ASN116
|
4.6
|
25.1
|
1.0
|
|
N
|
B:ASN116
|
4.6
|
25.7
|
1.0
|
|
NE2
|
B:HIS117
|
4.7
|
24.6
|
1.0
|
|
N
|
B:HIS252
|
4.9
|
22.1
|
1.0
|
|
Manganese binding site 4 out
of 8 in 1hpu
Go back to
Manganese Binding Sites List in 1hpu
Manganese binding site 4 out
of 8 in the 5'-Nucleotidase (Closed Form), Complex with Ampcp
 Mono view
 Stereo pair view
|
|
A full contact list of Manganese with other atoms in the Mn binding
site number 4 of 5'-Nucleotidase (Closed Form), Complex with Ampcp within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Mn601
b:45.4
occ:1.00
|
OD1
|
B:ASP41
|
2.1
|
19.1
|
1.0
|
|
O
|
B:HOH1690
|
2.1
|
23.3
|
1.0
|
|
OE1
|
B:GLN254
|
2.2
|
31.6
|
1.0
|
|
NE2
|
B:HIS43
|
2.3
|
20.1
|
1.0
|
|
OD2
|
B:ASP84
|
2.5
|
21.7
|
1.0
|
|
CG
|
B:ASP41
|
3.2
|
18.8
|
1.0
|
|
CD
|
B:GLN254
|
3.2
|
29.0
|
1.0
|
|
CE1
|
B:HIS43
|
3.2
|
19.5
|
1.0
|
|
CD2
|
B:HIS43
|
3.3
|
20.8
|
1.0
|
|
CG
|
B:ASP84
|
3.4
|
23.5
|
1.0
|
|
MN
|
B:MN600
|
3.4
|
24.0
|
1.0
|
|
CB
|
B:ASP84
|
3.6
|
19.9
|
1.0
|
|
O2B
|
B:A121603
|
3.7
|
29.6
|
1.0
|
|
CG
|
B:GLN254
|
3.7
|
26.1
|
1.0
|
|
CB
|
B:ASP41
|
3.7
|
17.4
|
1.0
|
|
O1B
|
B:A121603
|
4.1
|
27.1
|
1.0
|
|
O
|
B:HOH1723
|
4.1
|
39.4
|
1.0
|
|
O
|
B:HIS252
|
4.2
|
21.9
|
1.0
|
|
CE1
|
B:HIS217
|
4.2
|
23.0
|
1.0
|
|
OD2
|
B:ASP41
|
4.2
|
19.6
|
1.0
|
|
NE2
|
B:GLN254
|
4.3
|
27.3
|
1.0
|
|
NE2
|
B:HIS217
|
4.3
|
23.6
|
1.0
|
|
ND1
|
B:HIS43
|
4.4
|
21.0
|
1.0
|
|
CA
|
B:ASP41
|
4.4
|
19.2
|
1.0
|
|
CG
|
B:HIS43
|
4.5
|
20.3
|
1.0
|
|
CD2
|
B:HIS117
|
4.5
|
26.0
|
1.0
|
|
PB
|
B:A121603
|
4.5
|
27.9
|
1.0
|
|
CA
|
B:HIS252
|
4.5
|
22.9
|
1.0
|
|
OD1
|
B:ASP84
|
4.6
|
24.1
|
1.0
|
|
C
|
B:HIS252
|
4.8
|
23.1
|
1.0
|
|
ND1
|
B:HIS252
|
4.9
|
23.5
|
1.0
|
|
N
|
B:HIS252
|
5.0
|
22.1
|
1.0
|
|
O
|
B:HOH1768
|
5.0
|
36.7
|
1.0
|
|
Manganese binding site 5 out
of 8 in 1hpu
Go back to
Manganese Binding Sites List in 1hpu
Manganese binding site 5 out
of 8 in the 5'-Nucleotidase (Closed Form), Complex with Ampcp
 Mono view
 Stereo pair view
|
|
A full contact list of Manganese with other atoms in the Mn binding
site number 5 of 5'-Nucleotidase (Closed Form), Complex with Ampcp within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Mn600
b:20.0
occ:1.00
|
OD1
|
C:ASN116
|
2.2
|
19.9
|
1.0
|
|
O1B
|
C:A121604
|
2.2
|
24.7
|
1.0
|
|
NE2
|
C:HIS217
|
2.2
|
18.4
|
1.0
|
|
O
|
C:HOH1681
|
2.3
|
19.7
|
1.0
|
|
OD2
|
C:ASP84
|
2.3
|
19.6
|
1.0
|
|
ND1
|
C:HIS252
|
2.3
|
17.6
|
1.0
|
|
CE1
|
C:HIS252
|
3.0
|
22.4
|
1.0
|
|
CE1
|
C:HIS217
|
3.2
|
17.4
|
1.0
|
|
CG
|
C:ASP84
|
3.2
|
18.9
|
1.0
|
|
CG
|
C:ASN116
|
3.2
|
19.6
|
1.0
|
|
CD2
|
C:HIS217
|
3.3
|
19.8
|
1.0
|
|
CG
|
C:HIS252
|
3.4
|
20.3
|
1.0
|
|
MN
|
C:MN601
|
3.5
|
30.4
|
1.0
|
|
OD1
|
C:ASP84
|
3.5
|
21.6
|
1.0
|
|
PB
|
C:A121604
|
3.5
|
24.5
|
1.0
|
|
ND2
|
C:ASN116
|
3.6
|
20.9
|
1.0
|
|
CA
|
C:HIS252
|
3.8
|
19.9
|
1.0
|
|
O2B
|
C:A121604
|
3.9
|
23.2
|
1.0
|
|
CB
|
C:HIS252
|
3.9
|
20.9
|
1.0
|
|
CD2
|
C:HIS117
|
4.0
|
23.2
|
1.0
|
|
O
|
C:HOH1885
|
4.1
|
36.8
|
1.0
|
|
OD2
|
C:ASP41
|
4.1
|
18.8
|
1.0
|
|
NE2
|
C:HIS252
|
4.2
|
19.5
|
1.0
|
|
O
|
C:HIS252
|
4.3
|
21.1
|
1.0
|
|
ND1
|
C:HIS217
|
4.3
|
19.4
|
1.0
|
|
CG
|
C:HIS217
|
4.4
|
19.1
|
1.0
|
|
CD2
|
C:HIS252
|
4.5
|
19.4
|
1.0
|
|
CB
|
C:ASP84
|
4.5
|
20.5
|
1.0
|
|
O3B
|
C:A121604
|
4.5
|
25.7
|
1.0
|
|
N
|
C:ASN116
|
4.5
|
19.9
|
1.0
|
|
C
|
C:HIS252
|
4.6
|
21.1
|
1.0
|
|
CB
|
C:ASN116
|
4.6
|
19.3
|
1.0
|
|
C3A
|
C:A121604
|
4.6
|
27.6
|
1.0
|
|
NE2
|
C:HIS117
|
4.7
|
28.4
|
1.0
|
|
N
|
C:HIS252
|
4.8
|
18.7
|
1.0
|
|
Manganese binding site 6 out
of 8 in 1hpu
Go back to
Manganese Binding Sites List in 1hpu
Manganese binding site 6 out
of 8 in the 5'-Nucleotidase (Closed Form), Complex with Ampcp
 Mono view
 Stereo pair view
|
|
A full contact list of Manganese with other atoms in the Mn binding
site number 6 of 5'-Nucleotidase (Closed Form), Complex with Ampcp within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Mn601
b:30.4
occ:1.00
|
OD2
|
C:ASP41
|
2.1
|
18.8
|
1.0
|
|
O
|
C:HOH1681
|
2.2
|
19.7
|
1.0
|
|
OE1
|
C:GLN254
|
2.2
|
24.2
|
1.0
|
|
NE2
|
C:HIS43
|
2.2
|
20.6
|
1.0
|
|
OD2
|
C:ASP84
|
2.3
|
19.6
|
1.0
|
|
O
|
C:HOH1885
|
2.4
|
36.8
|
1.0
|
|
CE1
|
C:HIS43
|
3.0
|
22.8
|
1.0
|
|
CG
|
C:ASP41
|
3.3
|
20.2
|
1.0
|
|
CD
|
C:GLN254
|
3.3
|
24.9
|
1.0
|
|
CG
|
C:ASP84
|
3.3
|
18.9
|
1.0
|
|
CD2
|
C:HIS43
|
3.3
|
23.2
|
1.0
|
|
MN
|
C:MN600
|
3.5
|
20.0
|
1.0
|
|
CB
|
C:ASP84
|
3.5
|
20.5
|
1.0
|
|
CB
|
C:ASP41
|
3.8
|
20.7
|
1.0
|
|
CG
|
C:GLN254
|
3.9
|
24.2
|
1.0
|
|
O2B
|
C:A121604
|
3.9
|
23.2
|
1.0
|
|
O1B
|
C:A121604
|
4.1
|
24.7
|
1.0
|
|
ND1
|
C:HIS43
|
4.2
|
20.5
|
1.0
|
|
CE1
|
C:HIS217
|
4.2
|
17.4
|
1.0
|
|
CD2
|
C:HIS117
|
4.3
|
23.2
|
1.0
|
|
OD1
|
C:ASP41
|
4.3
|
20.6
|
1.0
|
|
O
|
C:HIS252
|
4.3
|
21.1
|
1.0
|
|
NE2
|
C:GLN254
|
4.4
|
24.2
|
1.0
|
|
CG
|
C:HIS43
|
4.4
|
21.8
|
1.0
|
|
NE2
|
C:HIS217
|
4.4
|
18.4
|
1.0
|
|
O
|
C:HOH1788
|
4.4
|
34.3
|
1.0
|
|
OD1
|
C:ASP84
|
4.4
|
21.6
|
1.0
|
|
CA
|
C:ASP41
|
4.5
|
18.4
|
1.0
|
|
PB
|
C:A121604
|
4.5
|
24.5
|
1.0
|
|
CA
|
C:HIS252
|
4.6
|
19.9
|
1.0
|
|
NE2
|
C:HIS117
|
4.8
|
28.4
|
1.0
|
|
C
|
C:HIS252
|
4.9
|
21.1
|
1.0
|
|
O3B
|
C:A121604
|
4.9
|
25.7
|
1.0
|
|
Manganese binding site 7 out
of 8 in 1hpu
Go back to
Manganese Binding Sites List in 1hpu
Manganese binding site 7 out
of 8 in the 5'-Nucleotidase (Closed Form), Complex with Ampcp
 Mono view
 Stereo pair view
|
|
A full contact list of Manganese with other atoms in the Mn binding
site number 7 of 5'-Nucleotidase (Closed Form), Complex with Ampcp within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Mn600
b:22.5
occ:1.00
|
OD1
|
D:ASN116
|
2.2
|
20.6
|
1.0
|
|
O
|
D:HOH1652
|
2.2
|
20.2
|
1.0
|
|
O1B
|
D:A121605
|
2.3
|
27.5
|
1.0
|
|
ND1
|
D:HIS252
|
2.3
|
24.2
|
1.0
|
|
OD2
|
D:ASP84
|
2.3
|
19.0
|
1.0
|
|
NE2
|
D:HIS217
|
2.3
|
23.6
|
1.0
|
|
CE1
|
D:HIS252
|
3.0
|
25.9
|
1.0
|
|
CG
|
D:ASN116
|
3.2
|
22.3
|
1.0
|
|
CG
|
D:ASP84
|
3.2
|
23.6
|
1.0
|
|
CD2
|
D:HIS217
|
3.3
|
23.6
|
1.0
|
|
CE1
|
D:HIS217
|
3.3
|
20.6
|
1.0
|
|
MN
|
D:MN601
|
3.4
|
36.7
|
1.0
|
|
CG
|
D:HIS252
|
3.5
|
23.8
|
1.0
|
|
OD1
|
D:ASP84
|
3.5
|
20.2
|
1.0
|
|
PB
|
D:A121605
|
3.6
|
27.8
|
1.0
|
|
ND2
|
D:ASN116
|
3.6
|
23.0
|
1.0
|
|
O2B
|
D:A121605
|
3.8
|
27.8
|
1.0
|
|
CA
|
D:HIS252
|
3.8
|
23.1
|
1.0
|
|
CB
|
D:HIS252
|
4.0
|
24.5
|
1.0
|
|
CD2
|
D:HIS117
|
4.0
|
22.7
|
1.0
|
|
OD2
|
D:ASP41
|
4.1
|
21.3
|
1.0
|
|
O
|
D:HOH1812
|
4.2
|
37.1
|
1.0
|
|
NE2
|
D:HIS252
|
4.2
|
23.2
|
1.0
|
|
O
|
D:HIS252
|
4.3
|
23.7
|
1.0
|
|
ND1
|
D:HIS217
|
4.4
|
21.8
|
1.0
|
|
CG
|
D:HIS217
|
4.4
|
23.2
|
1.0
|
|
CD2
|
D:HIS252
|
4.5
|
22.6
|
1.0
|
|
CB
|
D:ASP84
|
4.5
|
19.2
|
1.0
|
|
O3B
|
D:A121605
|
4.5
|
28.1
|
1.0
|
|
CB
|
D:ASN116
|
4.6
|
21.9
|
1.0
|
|
N
|
D:ASN116
|
4.6
|
21.1
|
1.0
|
|
C
|
D:HIS252
|
4.6
|
21.8
|
1.0
|
|
C3A
|
D:A121605
|
4.6
|
32.8
|
1.0
|
|
NE2
|
D:HIS117
|
4.7
|
23.7
|
1.0
|
|
N
|
D:HIS252
|
4.9
|
21.3
|
1.0
|
|
Manganese binding site 8 out
of 8 in 1hpu
Go back to
Manganese Binding Sites List in 1hpu
Manganese binding site 8 out
of 8 in the 5'-Nucleotidase (Closed Form), Complex with Ampcp
 Mono view
 Stereo pair view
|
|
A full contact list of Manganese with other atoms in the Mn binding
site number 8 of 5'-Nucleotidase (Closed Form), Complex with Ampcp within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Mn601
b:36.7
occ:1.00
|
OD2
|
D:ASP41
|
2.1
|
21.3
|
1.0
|
|
O
|
D:HOH1652
|
2.2
|
20.2
|
1.0
|
|
NE2
|
D:HIS43
|
2.2
|
20.6
|
1.0
|
|
OD2
|
D:ASP84
|
2.3
|
19.0
|
1.0
|
|
OE1
|
D:GLN254
|
2.3
|
24.2
|
1.0
|
|
O
|
D:HOH1812
|
2.5
|
37.1
|
1.0
|
|
CE1
|
D:HIS43
|
3.0
|
21.4
|
1.0
|
|
CG
|
D:ASP41
|
3.2
|
19.4
|
1.0
|
|
CG
|
D:ASP84
|
3.2
|
23.6
|
1.0
|
|
CD
|
D:GLN254
|
3.3
|
23.4
|
1.0
|
|
CD2
|
D:HIS43
|
3.4
|
17.6
|
1.0
|
|
MN
|
D:MN600
|
3.4
|
22.5
|
1.0
|
|
CB
|
D:ASP84
|
3.5
|
19.2
|
1.0
|
|
CB
|
D:ASP41
|
3.7
|
20.5
|
1.0
|
|
O2B
|
D:A121605
|
3.8
|
27.8
|
1.0
|
|
CG
|
D:GLN254
|
3.9
|
24.7
|
1.0
|
|
O1B
|
D:A121605
|
4.2
|
27.5
|
1.0
|
|
ND1
|
D:HIS43
|
4.2
|
20.2
|
1.0
|
|
CE1
|
D:HIS217
|
4.2
|
20.6
|
1.0
|
|
OD1
|
D:ASP41
|
4.3
|
21.3
|
1.0
|
|
O
|
D:HIS252
|
4.3
|
23.7
|
1.0
|
|
NE2
|
D:HIS217
|
4.3
|
23.6
|
1.0
|
|
CD2
|
D:HIS117
|
4.3
|
22.7
|
1.0
|
|
O
|
D:HOH1795
|
4.3
|
33.9
|
1.0
|
|
OD1
|
D:ASP84
|
4.4
|
20.2
|
1.0
|
|
NE2
|
D:GLN254
|
4.4
|
23.0
|
1.0
|
|
CG
|
D:HIS43
|
4.4
|
17.3
|
1.0
|
|
CA
|
D:ASP41
|
4.5
|
19.5
|
1.0
|
|
PB
|
D:A121605
|
4.6
|
27.8
|
1.0
|
|
CA
|
D:HIS252
|
4.6
|
23.1
|
1.0
|
|
C
|
D:HIS252
|
4.9
|
21.8
|
1.0
|
|
NE2
|
D:HIS117
|
4.9
|
23.7
|
1.0
|
|
Reference:
T.Knofel,
N.Strater.
Mechanism of Hydrolysis of Phosphate Esters By the Dimetal Center of 5'-Nucleotidase Based on Crystal Structures. J.Mol.Biol. V. 309 239 2001.
ISSN: ISSN 0022-2836
PubMed: 11491293
DOI: 10.1006/JMBI.2001.4656
Page generated: Sat Oct 5 10:54:02 2024
|
