Atomistry » Manganese » PDB 117e-1cev » 1ad4
Atomistry »
  Manganese »
    PDB 117e-1cev »
      1ad4 »

Manganese in PDB 1ad4: Dihydropteroate Synthetase Complexed with Oh-CH2-Pterin- Pyrophosphate From Staphylococcus Aureus

Enzymatic activity of Dihydropteroate Synthetase Complexed with Oh-CH2-Pterin- Pyrophosphate From Staphylococcus Aureus

All present enzymatic activity of Dihydropteroate Synthetase Complexed with Oh-CH2-Pterin- Pyrophosphate From Staphylococcus Aureus:
2.5.1.15;

Protein crystallography data

The structure of Dihydropteroate Synthetase Complexed with Oh-CH2-Pterin- Pyrophosphate From Staphylococcus Aureus, PDB code: 1ad4 was solved by C.Oefner, D.Kostrewa, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 13.00 / 2.40
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 65.748, 42.142, 99.040, 90.00, 106.06, 90.00
R / Rfree (%) 17.6 / n/a

Other elements in 1ad4:

The structure of Dihydropteroate Synthetase Complexed with Oh-CH2-Pterin- Pyrophosphate From Staphylococcus Aureus also contains other interesting chemical elements:

Potassium (K) 2 atoms

Manganese Binding Sites:

The binding sites of Manganese atom in the Dihydropteroate Synthetase Complexed with Oh-CH2-Pterin- Pyrophosphate From Staphylococcus Aureus (pdb code 1ad4). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 3 binding sites of Manganese where determined in the Dihydropteroate Synthetase Complexed with Oh-CH2-Pterin- Pyrophosphate From Staphylococcus Aureus, PDB code: 1ad4:
Jump to Manganese binding site number: 1; 2; 3;

Manganese binding site 1 out of 3 in 1ad4

Go back to Manganese Binding Sites List in 1ad4
Manganese binding site 1 out of 3 in the Dihydropteroate Synthetase Complexed with Oh-CH2-Pterin- Pyrophosphate From Staphylococcus Aureus


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Dihydropteroate Synthetase Complexed with Oh-CH2-Pterin- Pyrophosphate From Staphylococcus Aureus within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mn268

b:42.3
occ:1.00
O B:HOH423 2.1 65.2 1.0
O A:HOH413 2.2 43.9 1.0
NE2 A:HIS264 2.4 36.7 1.0
O B:HOH422 2.4 67.2 1.0
CD2 A:HIS264 3.0 28.7 1.0
CE1 A:HIS264 3.5 38.6 1.0
OD2 B:ASP187 4.0 26.8 1.0
CG A:HIS264 4.2 39.1 1.0
OD1 B:ASP187 4.3 22.7 1.0
ND1 A:HIS264 4.4 40.2 1.0
OE2 B:GLU188 4.5 17.4 1.0
CG B:ASP187 4.5 23.2 1.0

Manganese binding site 2 out of 3 in 1ad4

Go back to Manganese Binding Sites List in 1ad4
Manganese binding site 2 out of 3 in the Dihydropteroate Synthetase Complexed with Oh-CH2-Pterin- Pyrophosphate From Staphylococcus Aureus


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Dihydropteroate Synthetase Complexed with Oh-CH2-Pterin- Pyrophosphate From Staphylococcus Aureus within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mn269

b:37.7
occ:1.00
O6P A:HH2271 2.0 16.8 1.0
O A:HOH407 2.3 34.6 1.0
O A:HOH362 2.3 29.3 1.0
OD1 A:ASN11 2.4 34.0 1.0
P2 A:HH2271 3.5 18.1 1.0
O2P A:HH2271 3.6 14.8 1.0
CG A:ASN11 3.6 28.4 1.0
NH2 A:ARG239 4.1 9.9 1.0
O3P A:HH2271 4.1 14.1 1.0
O A:HOH406 4.1 23.5 1.0
O A:VAL49 4.2 29.8 1.0
O A:HOH326 4.2 18.1 1.0
O4 A:HH2271 4.2 11.7 1.0
P1 A:HH2271 4.2 15.1 1.0
O5P A:HH2271 4.3 1.1 1.0
ND2 A:ASN11 4.3 26.4 1.0
C3 A:HH2271 4.4 14.6 1.0
O4P A:HH2271 4.5 11.1 1.0
OD2 A:ASP84 4.7 22.0 1.0
CB A:ASN11 4.8 21.2 1.0
O A:GLY47 4.8 23.4 1.0
C A:GLY47 4.9 19.6 1.0

Manganese binding site 3 out of 3 in 1ad4

Go back to Manganese Binding Sites List in 1ad4
Manganese binding site 3 out of 3 in the Dihydropteroate Synthetase Complexed with Oh-CH2-Pterin- Pyrophosphate From Staphylococcus Aureus


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 3 of Dihydropteroate Synthetase Complexed with Oh-CH2-Pterin- Pyrophosphate From Staphylococcus Aureus within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mn1

b:27.9
occ:1.00
O A:HOH372 2.1 34.5 1.0
NE2 B:HIS264 2.2 20.4 1.0
O A:HOH357 2.3 16.0 1.0
O B:HOH416 2.3 29.1 1.0
O B:HOH417 2.5 37.8 1.0
CD2 B:HIS264 3.0 11.2 1.0
CE1 B:HIS264 3.3 15.3 1.0
OD2 A:ASP187 4.1 19.7 1.0
CG B:HIS264 4.2 13.6 1.0
OD1 A:ASP187 4.2 21.9 1.0
OE2 A:GLU188 4.2 6.3 1.0
ND1 B:HIS264 4.2 11.5 1.0
CG A:ASP187 4.6 16.3 1.0
O A:ALA184 4.8 10.3 1.0
O A:HOH288 4.9 12.9 1.0

Reference:

I.C.Hampele, A.D'arcy, G.E.Dale, D.Kostrewa, J.Nielsen, C.Oefner, M.G.Page, H.J.Schonfeld, D.Stuber, R.L.Then. Structure and Function of the Dihydropteroate Synthase From Staphylococcus Aureus. J.Mol.Biol. V. 268 21 1997.
ISSN: ISSN 0022-2836
PubMed: 9149138
DOI: 10.1006/JMBI.1997.0944
Page generated: Tue Dec 15 03:46:05 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy