Manganese in PDB 8v7k: Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 10 Mm MN2+ For 1800S

All present enzymatic activity of Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 10 Mm MN2+ For 1800S:
2.7.7.7;

The structure of Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 10 Mm MN2+ For 1800S, PDB code: 8v7k was solved by C.Chang, Y.Gao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.81 / 1.65
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	98.52, 98.52, 81.652, 90, 90, 120
R / Rfree (%)	20.6 / 23.3

The binding sites of Manganese atom in the Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 10 Mm MN2+ For 1800S (pdb code 8v7k). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 10 Mm MN2+ For 1800S, PDB code: 8v7k:
Jump to Manganese binding site number: 1; 2;

Manganese binding site 1 out of 2 in the Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 10 Mm MN2+ For 1800S


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 10 Mm MN2+ For 1800S within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn501 b:28.1 occ:0.80 OD1 A:ASP13 2.0 28.4 1.0 OD2 A:ASP115 2.0 37.0 1.0 O2G A:DTP503 2.1 32.8 0.8 O1B A:DTP503 2.2 26.1 0.8 O A:MET14 2.2 29.0 1.0 O1A A:DTP503 2.3 32.4 0.8 CG A:ASP13 3.0 34.1 1.0 PB A:DTP503 3.2 32.3 0.8 CG A:ASP115 3.2 34.9 1.0 C A:MET14 3.4 25.3 1.0 PG A:DTP503 3.4 32.7 0.8 PA A:DTP503 3.4 39.8 0.8 OD2 A:ASP13 3.4 38.6 1.0 O3A A:DTP503 3.4 36.6 0.8 MN A:MN502 3.6 29.3 0.7 O3B A:DTP503 3.6 31.1 0.8 OD1 A:ASP115 3.8 36.5 1.0 N A:MET14 3.9 21.2 1.0 C5' A:DTP503 4.0 33.3 0.8 O3G A:DTP503 4.0 31.1 0.8 C A:ASP13 4.2 19.5 1.0 CA A:MET14 4.2 19.3 1.0 NZ A:LYS231 4.2 34.5 1.0 O5' A:DTP503 4.2 35.4 0.8 N A:ASP15 4.3 22.8 1.0 CB A:ASP13 4.3 27.1 1.0 N A:CYS16 4.3 23.4 1.0 O A:HOH629 4.3 31.9 0.7 CB A:ASP115 4.3 23.6 1.0 CA A:ASP15 4.4 23.1 1.0 O2B A:DTP503 4.5 30.5 0.8 O1G A:DTP503 4.5 31.3 0.8 C A:ASP15 4.6 22.6 1.0 O A:ASP13 4.6 20.5 1.0 O2A A:DTP503 4.6 37.4 0.8 O A:ASP115 4.6 25.9 1.0 CA A:ASP13 4.7 21.3 1.0 N A:PHE17 4.7 21.1 1.0 CB A:MET14 4.9 27.4 1.0 CB A:PHE17 5.0 20.2 1.0

Manganese binding site 2 out of 2 in the Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 10 Mm MN2+ For 1800S


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 10 Mm MN2+ For 1800S within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn502 b:29.3 occ:0.70 O A:HOH629 2.1 31.9 0.7 OE1 A:GLU116 2.1 46.0 1.0 OD2 A:ASP13 2.1 38.6 1.0 O1A A:DTP503 2.2 32.4 0.8 OD1 A:ASP115 2.3 36.5 1.0 O3' P:CAR9 2.4 39.7 0.7 CD A:GLU116 3.0 41.4 1.0 CG A:ASP115 3.1 34.9 1.0 CG A:ASP13 3.2 34.1 1.0 OD2 A:ASP115 3.2 37.0 1.0 C3' P:CAR9 3.4 41.2 0.7 PA A:DTP503 3.4 39.8 0.8 OD1 A:ASP13 3.6 28.4 1.0 MN A:MN501 3.6 28.1 0.8 OE2 A:GLU116 3.7 39.6 1.0 O2A A:DTP503 3.7 37.4 0.8 CB A:GLU116 3.9 32.4 1.0 CG A:GLU116 3.9 27.7 1.0 O5' A:DTP503 4.0 35.4 0.8 OG A:SER113 4.0 31.1 1.0 C4' P:CAR9 4.1 42.2 0.7 C5' A:DTP503 4.3 33.3 0.8 NZ A:LYS224 4.3 42.4 1.0 CB A:ASP13 4.4 27.1 1.0 O A:ASP115 4.4 25.9 1.0 C A:ASP115 4.5 28.0 1.0 CB A:ASP115 4.5 23.6 1.0 O3' P:CAR9 4.6 42.9 0.3 C2' P:CAR9 4.6 43.5 0.7 O2G A:DTP503 4.7 32.8 0.8 O3A A:DTP503 4.7 36.6 0.8 N A:GLU116 4.7 23.4 1.0 O5' P:CAR9 4.9 46.5 0.7 CA A:GLU116 4.9 28.6 1.0 O1B A:DTP503 5.0 26.1 0.8

C.Chang, Y.Gao. Human Dna Polymerase Eta-Dna-Arac-Ended Primer Ternary Complex:Reaction with 10 Mm MN2+ For 1800S To Be Published.